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Cat. No.: HY-163326

Tyrosinase-IN-25

Tyrosinase-IN-25 (compound 1l) is an inhibitor of tyrosinase and melanin biosynthesis in human melanoma cells.

For research use only. We do not sell to patients.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Tyrosinase-IN-25 (compound 1l) is an inhibitor of tyrosinase and melanin biosynthesis in human melanoma cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MNT-1	CC₅₀	>100 μM Compound: 1l	Cytotoxicity against human MNT-1 cells incubated for 4 days by resazurin assay Cytotoxicity against human MNT-1 cells incubated for 4 days by resazurin assay	[PMID: 38262119]
MNT-1	CC₅₀	67 μM Compound: 1l	Cytotoxicity against human MNT-1 cells incubated for 14 days by resazurin assay Cytotoxicity against human MNT-1 cells incubated for 14 days by resazurin assay	[PMID: 38262119]
MNT-1	IC₅₀	19 μM Compound: 1l	Inhibition of melanogenesis in human MNT-1 cells incubated for 4 days Inhibition of melanogenesis in human MNT-1 cells incubated for 4 days	[PMID: 38262119]
MNT-1	IC₅₀	3.3 μM Compound: 1l	Inhibition of melanogenesis in human MNT-1 cells incubated for 14 days Inhibition of melanogenesis in human MNT-1 cells incubated for 14 days	[PMID: 38262119]

Molecular Weight 309.32
Formula C₁₈H₁₅NO₄
SMILES

CC(NC1=CC=CC(C/2=O)=C1CC2=C/C3=C(O)C=C(O)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.