Search Result

Results for "

Methylsulfonyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (2) Androgen Receptor (1) Antibiotic (4) Bacterial (6) Bcl-2 Family (1) Beta-lactamase (2) Biochemical Assay Reagents (3) CD38 (1) Cholecystokinin Receptor (1) CRFR (2) Drug Intermediate (8) Endogenous Metabolite (1) Ferroportin (1) Isotope-Labeled Compounds (6) MMP (1) Nucleoside Antimetabolite/Analog (1) PROTAC Linkers (3) Reactive Oxygen Species (ROS) (1) Reference Standards (6) Vasopressin Receptor (1) Virus Protease (1)
By Research Areas:	Cancer (5) Infection (9) Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (3)
Oligonucleotides:	Nucleoside Analogs (1) Uridine (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-B0479

Thiamphenicol Thiophenicol; Dextrosulphenidol	Beta-lactamase Bacterial Antibiotic	Infection
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-P1108

Astressin 2B 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-I0616

*(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine*	Drug Intermediate	Others
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine is a drug intermediate for synthesis of various active compounds.

HY-B0479S

Thiamphenicol-d3 Thiophenicol-d₃; Dextrosulphenidol-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-A0248AS

Polymyxin B1-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-B0784

*2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole benzenesulfonate*	Drug Intermediate	Others
2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole benzenesulfonate is a drug intermediate for synthesis of various active compounds.

HY-I0638

*1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine*	Drug Intermediate	Others
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine is a drug intermediate for synthesis of various active compounds.

HY-B0479R

Thiamphenicol (Standard) Thiophenicol (Standard); Dextrosulphenidol (Standard)	Beta-lactamase Reference Standards Bacterial Antibiotic	Infection
Thiamphenicol (Standard) is the analytical standard of Thiamphenicol. This product is intended for research and analytical applications. Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-79681

*2-Chloro-N-(methylsulfonyl)acetamide*	Drug Intermediate	Others
2-Chloro-N-(methylsulfonyl)acetamide is a drug intermediate for synthesis of various active compounds.

HY-W001461

*tert-Butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate*	PROTAC Linkers	Cancer
tert-Butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-77024

*2,2,2-Trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethanone* Odanacatib intermediate	Drug Intermediate	Others
2,2,2-Trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethanone (Odanacatib intermediate) is a drug intermediate for synthesis of various active compounds.

HY-I0616A

*(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine*	Drug Intermediate	Others
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine is a drug intermediate for synthesis of various active compounds.

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-77642

*4-(Methylsulfonyl)phenylboronic acid*	Biochemical Assay Reagents Drug Intermediate	Metabolic Disease
4-(Methylsulfonyl)phenylboronic acid is an intermediate. 4-(Methylsulfonyl)phenylboronic acid can be used to synthesize GPR119 agonists via Suzuki coupling reaction. 4-(Methylsulfonyl)phenylboronic acid can be used in the research of type 2 diabetes .

HY-W141922

*N-(Methylsulfonyl)glycine*	Amino Acid Derivatives	Others
N-(Methylsulfonyl)glycine is a Glycine (HY-Y0966) derivative .

HY-W334976

*Tert-butyl 3-(((methylsulfonyl)oxy)methyl)azetidine-1-carboxylate*	PROTAC Linkers	Cancer
Tert-butyl 3-(((methylsulfonyl)oxy)methyl)azetidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W141391

*tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate*	PROTAC Linkers	Cancer
tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-34392

*4'-(Methylsulfonyl)acetophenone*	Biochemical Assay Reagents	Others
p-Methylsulfonylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-139032

CM121	Aldehyde Dehydrogenase (ALDH)	Others
CM121 is an active site-directed reversible ALDH1A2 inhibitor (IC₅₀=0.54 μM；Kd=1.1 μM) with a variety of hydrophobic interactions .

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-152323

*N1-Methylsulfonyl* pseudouridine**	Nucleoside Antimetabolite/Analog	Others
N1-Methylsulfonyl pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W319374

*2-(Methylsulfonyl)ethyl* n-succinimidyl carbonate**	Biochemical Assay Reagents	Others
2-(Methylsulfonyl)ethyl n-succinimidyl carbonate is a protein crosslinker. 2-(Methylsulfonyl)ethyl n-succinimidyl carbonate has amino protective function .

HY-157386S

*8-(o-Fluoro-benzyl)theophylline methylsulfonyl-13C2*	Isotope-Labeled Compounds	Others
8-(o-Fluoro-benzyl)theophylline methylsulfonyl- ¹³C2 is a ¹³C labeled 8-(o-Fluoro-benzyl)theophylline methylsulfonyl.

HY-I0616R

*(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (Standard)*	Reference Standards
(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (Standard) is the analytical standard of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine. This product is intended for research and analytical applications.

HY-42938

*(S)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride*	Amino Acid Derivatives	Others
(S)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride is a phenylalanine derivative .

HY-176863

*Di(5-(methylsulfonyl)-1,3,4-oxadiazol-2-yl)-benzene-amide-PEG4-ester-2,3,5,6-F-Ph*	Androgen Receptor	Neurological Disease
Di(5-(methylsulfonyl)-1,3,4-oxadiazol-2-yl)-benzene-amide-PEG4-ester-2,3,5,6-F-Ph (Compound L-1026) is a linker that connects Androgen Receptor (AR) RNAi agent to targeting ligands (such as antibodies). The conjugation can inhibit AR gene expression and reduce AR activity. Di(5-(methylsulfonyl)-1,3,4-oxadiazol-2-yl)-benzene-amide-PEG4-ester-2,3,5,6-F-Ph can be used for spinal and bulbar muscular atrophy (SBMA) research .

HY-W742886

Dideschloro Florfenicol-d3	Isotope-Labeled Compounds	Others
Dideschloro Florfenicol-d₃ is the deuterium labeled Acetamide, N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R,S)]- (HY-W587855).

HY-116974

ent-Thiamphenicol ent-Thiophenicol; ent-Dextrosulphenidol	Antibiotic	Others
ent-Thiamphenicol (ent-Dextrosulphenidol) is a enantiomer of Thiamphenicol (HY-B0479). Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-B0479S1

Thiamphenicol-d3-1 Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1	Isotope-Labeled Compounds	Infection
Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria) .

HY-P2592

Ro 23-7014	Cholecystokinin Receptor	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

HY-P10386

155H1	Bcl-2 Family	Cancer
155H1 (Compound 11) is a stapled peptide, that covalently binds hMcl1 (172-323) with IC₅₀ of 18 nM .

HY-Z8577

Nimesulide impurity 6 N-Methylsulfonyl Nimesulide	Drug Intermediate	Others
Nimesulide impurity 6 (N-Methylsulfonyl Nimesulide) is an impurity of Nimesulide.

HY-Z0054R

Methyl phenyl sulfone (Standard)	Reference Standards
(Methylsulfonyl)benzene (Standard) is the analytical standard of (Methylsulfonyl)benzene. This product is intended for research and analytical applications.

HY-23529R

Lifitegrast impurity 6 (Standard)	Reference Standards
(S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic acid (Standard) is the analytical standard of (S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic acid. This product is intended for research and analytical applications.

HY-Z0791R

Lifitegrast impurity 4 hydrochloride (Standard)	Reference Standards
Benzyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride (Standard) is the analytical standard of Benzyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride. This product is intended for research and analytical applications.

HY-Z0747R

Apremilast impurity 66 (Standard)	Reference Standards
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanol (Standard) is the analytical standard of 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanol. This product is intended for research and analytical applications.

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	상품명	Type

HY-77642

*4-(Methylsulfonyl)phenylboronic acid*	Biochemical Assay Reagents
4-(Methylsulfonyl)phenylboronic acid is an intermediate. 4-(Methylsulfonyl)phenylboronic acid can be used to synthesize GPR119 agonists via Suzuki coupling reaction. 4-(Methylsulfonyl)phenylboronic acid can be used in the research of type 2 diabetes .

HY-34392

*4'-(Methylsulfonyl)acetophenone*	Biochemical Assay Reagents
p-Methylsulfonylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	상품명	Target	Research Area

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-P1108

Astressin 2B 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-A0248AS

Polymyxin B1-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-W141922

*N-(Methylsulfonyl)glycine*	Amino Acid Derivatives	Others
N-(Methylsulfonyl)glycine is a Glycine (HY-Y0966) derivative .

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-42938

*(S)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride*	Amino Acid Derivatives	Others
(S)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride is a phenylalanine derivative .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2592

Ro 23-7014	Cholecystokinin Receptor	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

HY-P10386

155H1	Bcl-2 Family	Cancer
155H1 (Compound 11) is a stapled peptide, that covalently binds hMcl1 (172-323) with IC₅₀ of 18 nM .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-A0248AS

Polymyxin B1-d7 TFA	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Isotope-Labeled Compounds Bacterial
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Isotope-Labeled Compounds Bacterial
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	상품명	Chemical Structure

HY-B0479S

Thiamphenicol-d3
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-A0248AS

Polymyxin B1-d7 TFA

Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-157386S

*8-(o-Fluoro-benzyl)theophylline methylsulfonyl-13C2*
8-(o-Fluoro-benzyl)theophylline methylsulfonyl- ¹³C2 is a ¹³C labeled 8-(o-Fluoro-benzyl)theophylline methylsulfonyl.

HY-W742886

Dideschloro Florfenicol-d3
Dideschloro Florfenicol-d₃ is the deuterium labeled Acetamide, N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R,S)]- (HY-W587855).

HY-B0479S1

Thiamphenicol-d3-1

Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria) .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA

Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	상품명		Classification

HY-152323

*N1-Methylsulfonyl* pseudouridine**		Nucleoside Analogs Uridine
N1-Methylsulfonyl pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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Methylsulfonyl

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