1. GPCR/G Protein
  2. Vasopressin Receptor
  3. SKF 100398

SKF 100398 (Synonyms: d(CH2)5Tyr(Et)VAVP)

Cat. No.: HY-P3066 Purity: >98.0%
Handling Instructions

SKF 100398 (d(CH2)5Tyr(Et)VAVP) is an arginine vasopressin (AVP) analogue, and acts as a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

SKF 100398 Chemical Structure

SKF 100398 Chemical Structure

CAS No. : 77453-01-1

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Description

SKF 100398 (d(CH2)5Tyr(Et)VAVP) is an arginine vasopressin (AVP) analogue, and acts as a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP[1].

In Vivo

SKF 100398 is a specific antagonist of the hydrosmotic effect of exogenous and endogenous AVP[1].
SKF 100398 (8 μg/kg; i.v.) abolishes the antidiuretic effect of AVP[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (250-300 g)[1]
Dosage: 8 μg/kg
Administration: Intravenous injection
Result: Completely blocked the antidiuretic effect of exogenous AVP (4 ng/kg body wt i.v.).
Molecular Weight

1136.39

Formula

C₅₃H₇₇N₁₃O₁₁S₂

CAS No.

77453-01-1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
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Keywords:

SKF 100398d(CH2)5Tyr(Et)VAVPSKF100398SKF-100398Vasopressin ReceptorargininevasopressinanalogueantidiureticactionInhibitorinhibitorinhibit

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SKF 100398
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HY-P3066
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