Search Result

Results for "

TAN

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Antibiotic (9) Apoptosis (5) Autophagy (5) Bacterial (6) CGRP Receptor (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Endothelin Receptor (1) Environmental Pollutants (1) Fungal (1) iGluR (1) Isotope-Labeled Compounds (2) Opioid Receptor (3) PROTAC Linkers (1) RAR/RXR (5) Reactive Oxygen Species (ROS) (1) Reference Standards (3) TNF Receptor (1) VEGFR (2) β-glucuronidase (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (2) Infection (10) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (9)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0135

Tanshinone IIA 35+ Cited Publications Dan Shen ketone	VEGFR	Cardiovascular Disease Cancer
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-A0067

Oxybenzone 5+ Cited Publications Benzophenone 3	Environmental Pollutants Autophagy RAR/RXR Apoptosis	Neurological Disease
Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-108365

Gamithromycin ML-1709460	Bacterial Antibiotic	Infection
Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively.

HY-N16039

TAN-1030A	β-glucuronidase	Inflammation/Immunology
TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice .

HY-136208

TAN-452	Opioid Receptor	Neurological Disease
TAN-452 is an orally active, selective peripherally acting δ-opioid receptor (DOR) antagonist with a K_i of 0.47 nM and a K_b of 0.21 nM. TAN-452 is an antagonist for μ-opioid receptor (MOR; K_i=36.56 nM and K_b=9.43 nM) and κ-opioid receptor (KOR; K_i=5.31 nM and K_b=7.18 nM). TAN-452, a derivative of Naltrindole, demonstrates low brain penetrability and attenuates morphine-induced side effects without affecting pain control .

HY-121300

Kendomycin (-)-TAN2162	Antibiotic Bacterial Endothelin Receptor CGRP Receptor	Infection Cancer
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent .

HY-W003511

tans-4-Hydroxy-D-proline hydrochloride	ADC Linker PROTAC Linkers	Cancer
tans-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR

HY-101317

TAN-67 dihydrobromide 1 Publications Verification SB-205607 dihydrobromide	Opioid Receptor	Neurological Disease
TAN-67 (SB-205607) dihydrobromide is a potent and selective nonpeptidic δ-opioid receptor agonist with a K_i value of 0.647 nM. TAN-67 dihydrobromide has neuroprotective effect. TAN-67 dihydrobromide can be used in research of ischemic stroke .

HY-A0067S

Oxybenzone-d5	RAR/RXR Apoptosis Autophagy	Neurological Disease
Oxybenzone-d₅ is the deuterium labeled Oxybenzone . Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-101317A

TAN-67 SB-205607	Opioid Receptor	Metabolic Disease
TAN-67 (SB-205607) is a non-peptidic delta-opioid receptor agonist that exhibits significant antinociceptive activity in both diabetic and non-diabetic mice. TAN-67 demonstrates a marked and dose-dependent reduction in acetic acid-induced abdominal constrictions, with a notably stronger effect in diabetic mice compared to their non-diabetic counterparts. TAN-67's antinociceptive properties are primarily mediated through the activation of delta 1-opioid receptors, as indicated by the pronounced antagonism observed upon administration of a selective delta 1-opioid receptor antagonist.

HY-105476

TAN 950A	Antibiotic Fungal iGluR	Infection Neurological Disease
TAN 950A is antifungal amino acid antibiotic. TAN 950A has affinity for three excitatory amino acid (EAA) receptor and can inhibit [3H]AMPA, [3H]kainite and [3H]CPP binding competitively. TAN 950A can be used for the researches of infection and neurological disease .

HY-119843

Asterric Acid Dimethylosoic acid; RES-1214-1; TAN 1415A	Antibiotic	Infection
Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.

HY-N0135R

Tanshinone IIA (Standard) Dan Shen ketone (STANdard)	Reference Standards VEGFR	Cardiovascular Disease Cancer
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-A0067R

Oxybenzone (Standard) Benzophenone 3 (STANdard)	Reference Standards RAR/RXR Autophagy Apoptosis	Neurological Disease
Oxybenzone (Standard) is the analytical standard of Oxybenzone. This product is intended for research and analytical applications. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-W747504

TAN-420E Dihydroherbimycin A	Antibiotic Reactive Oxygen Species (ROS)	Infection Cancer
TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC₅₀ of 1.3 μM .

HY-128488

*Antibiotic TAN-592B*	Bacterial Antibiotic	Infection
Antibiotic TAN-592B is an antibiotic against infectious disease caused by bacteria .

HY-167651

TAN-1057C	Bacterial Antibiotic	Infection
TAN-1057C is a potent antibiotic which exhibits antibacterial activity against Gram-negative and Gram-positive bacteria, including Methicillin (HY-121544)-resistant Staphylococcus aureus .

HY-111134

TAN 420C	Antibiotic	Infection Cancer
TAN 420C is an antibiotic that shows a strong cytotoxic activity against the lymphocytic leukemia .

HY-126699

Herbimycin C Antibiotic TAN 420D	Bacterial	Infection
Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC₅₀s=7.3 and 1.2 μg/mL, respectively).

HY-108365R

Gamithromycin (Standard) ML-1709460 (STANdard)	Bacterial Antibiotic Reference Standards	Infection
Gamithromycin (Standard) is the analytical standard of Gamithromycin. This product is intended for research and analytical applications. Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively.

HY-163941

GSK_WRN2	DNA/RNA Synthesis	Cancer
GSK_WRN2 is a potent and selective covalent WRN helicase inhibitor that suppresses replication stress caused by DNA (TA)_n dinucleotide repeat expansions. GSK_WRN2 can be used to study microsatellite instability (MSI) cancers .

HY-180420

Tan-931	Cytochrome P450	Cancer
Tan-931 is a non-competitive and selective inhibitor of aromatase , with an IC₅₀ is 17.2 μM and a K_i of 40 μM for human aromatase, and an IC₅₀ of 162 μM for rat aromatase. Tan-931 reduces plasma estradiol-17β level and weight of ovaries and uterus in PMSG (HY-N12634)-treated female rats. Tan-931 can be used for the research of estrogen-dependent metastatic breast cancer .

HY-A0067S1

Oxybenzone-13C6 Benzophenone 3-13C₆	Isotope-Labeled Compounds RAR/RXR Autophagy Apoptosis	Neurological Disease
Oxybenzone- ¹³C₆ (Benzophenone 3- ¹³C₆) is the ¹³C-labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-W653958

Oxybenzone-d3 Benzophenone 3-d₃	Isotope-Labeled Compounds RAR/RXR Autophagy Apoptosis	Neurological Disease
Oxybenzone-d₃ (Benzophenone 3-d₃) is a deuterium labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-P991809

*Anti-Mouse CD70 Antibody (TAN* 1-7)**	TNF Receptor	Inflammation/Immunology
Anti-Mouse CD70 Antibody (TAN 1-7) reacts with the mouse CD70. Anti-Mouse CD70 Antibody (TAN 1-7) is a non-depleting antibody which blocks the CD70-CD27 interaction. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679).

Cat. No.	Product Name	Target	Research Area

HY-P2111

Achatin I	Peptides	Neurological Disease
Achatin I is a neuroexcitatory tetrapeptide. Achatin I can be derived from Achatina fulica férussac. Achatin-I induces a voltage-dependent inward current. Achatin-I shows marked excitatory effects on the three Achatina giant neurones, PON, TAN and V-RCDN .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991809

*Anti-Mouse CD70 Antibody (TAN* 1-7)**	TNF Receptor	Inflammation/Immunology
Anti-Mouse CD70 Antibody (TAN 1-7) reacts with the mouse CD70. Anti-Mouse CD70 Antibody (TAN 1-7) is a non-depleting antibody which blocks the CD70-CD27 interaction. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0135

Tanshinone IIA 35+ Cited Publications Dan Shen ketone	Quinones Classification of Application Fields Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants Naphthalene Quinones Disease Research Fields Source Classification Cancer	VEGFR
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-N16039

TAN-1030A	Alkaloids Microorganisms Indole Alkaloids Source Classification	β-glucuronidase
TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice .

HY-N0135R

Tanshinone IIA (Standard) Dan Shen ketone (STANdard)	Quinones Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants Naphthalene Quinones Source Classification	Reference Standards VEGFR
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-W747504

TAN-420E Dihydroherbimycin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Reactive Oxygen Species (ROS)
TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC₅₀ of 1.3 μM .

HY-111134

TAN 420C	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Disease Research Fields Other Antibiotics Source Classification Cancer	Antibiotic
TAN 420C is an antibiotic that shows a strong cytotoxic activity against the lymphocytic leukemia .

HY-180420

Tan-931	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Cytochrome P450
Tan-931 is a non-competitive and selective inhibitor of aromatase , with an IC₅₀ is 17.2 μM and a K_i of 40 μM for human aromatase, and an IC₅₀ of 162 μM for rat aromatase. Tan-931 reduces plasma estradiol-17β level and weight of ovaries and uterus in PMSG (HY-N12634)-treated female rats. Tan-931 can be used for the research of estrogen-dependent metastatic breast cancer .

Species:	Human (3) Virus (1)
Tag:	His (4) Avi (2)
Source:	HEK293 (3) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76005

	RVFV-L Protein (His) Rift Valley fever virus (TAN/Dod-002/07) RVFV-L Protein (His)	Virus	E. coli
	RVFV-L Protein (His) is the recombinant Virus-derived RVFV-L protein, expressed by E. coli, with C-His labeled tag.

HY-P704827

	NOTCH1 Protein, Human (HEK293, His) Notch-1; TAN1; NOTCH1; 9930111A19Rik; lin-12; Mis6; N1	Human	HEK293
	NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (HEK293, His) is the recombinant human-derived NOTCH1 protein, expressed by HEK293, with C-His labeled tag.

HY-P78501

	NOTCH1 Protein, Human (HEK293, His-Avi) Notch-1; TAN1; NOTCH1; 9930111A19Rik; lin-12; Mis6; N1	Human	HEK293
	NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived NOTCH1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78184

	NOTCH1 Protein, Human (Biotinylated, HEK293, His-Avi) Notch-1; TAN1; NOTCH1; 9930111A19Rik; lin-12; Mis6; N1	Human	HEK293
	NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived NOTCH1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-A0067S

Oxybenzone-d5
Oxybenzone-d₅ is the deuterium labeled Oxybenzone . Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-A0067S1

Oxybenzone-13C6
Oxybenzone- ¹³C₆ (Benzophenone 3- ¹³C₆) is the ¹³C-labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

Oxybenzone-13C6

Oxybenzone- ¹³C₆ (Benzophenone 3- ¹³C₆) is the ¹³C-labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

HY-W653958

Oxybenzone-d3

Oxybenzone-d₃ (Benzophenone 3-d₃) is a deuterium labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Rat (2) Mouse (4) Monkey (2)
Application:	IHC-P (4) ICC/IF (4) IP (1) WB (2) FC (1) ELISA (1)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4) Biotin (1)
Clonality:	Polyclonal (1) Monoclonal (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88715

	THUMPD1 Antibody (YA8399) TAN1	IHC-P, ICC/IF	Human, Monkey, Mouse
	THUMPD1 Antibody (YA8399) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to THUMPD1.

HY-P88715A

	THUMPD1 Antibody (YA8399)(PBS only) TAN1	IHC-P, ICC/IF	Human, Monkey, Mouse
	THUMPD1 Antibody (YA8399) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to THUMPD1.

HY-P80768

	Notch1 Antibody 1 Publications Verification NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Notch1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Notch1.

HY-P86591

	Notch1 Antibody (YA6283) NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Notch1 Antibody (YA6283) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Notch1.