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Results for "

TNFSF13

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (2) TNF Receptor (1)
By Research Areas:	Inflammation/Immunology (1)

Inhibitors & Agonists

Screening Libraries

Inhibitory Antibodies

Recombinant Proteins

Antibodies

TNFSF13 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TNFSF13 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TNFSF13B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TNFSF13B Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF13B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Zigakibart BION-1301	TNF Receptor	Inflammation/Immunology
Zigakibart (BION-1301) is an IgG4-kappa, anti-TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256) humanized monoclonal antibody. Zigakibart shows anti-inflammatory activity .

Cat. No.	Product Name

HY-L156

Autoimmune Disease Compound Library	461 compounds
Autoimmune disease is a pathological disease characterized by inflammatory disorders targeting autoantigens. The routine treatment of autoimmune diseases suppresses general immune function to regulate uncontrolled inflammation. The current targeted immunotherapy suppresses the main pro-inflammatory signaling pathways by blocking inflammatory cytokines, cell surface molecules, and intracellular kinases. As key participants in innate immunity, macrophages and dendritic cells (DCs) are crucial for Ag presentation and pro-inflammatory cytokine production, such as TNF and IL-1 β、 IL-6, IL-23, B cell activating factor (BAFF), and the proliferation-inducing ligand (APRIL, also known as TNFSF13A). MCE designs a unique collection of 461 autoimmune disease-related compounds, covering multiple targets and subtypes, such as TNF Receptor, IFNAR, JAK, Btk, TLR, IL-6, IL-17, IL-23, etc. It is a useful tool for screening autoimmune disease drugs.

Autoimmune Disease Compound Library

461 compounds

Autoimmune disease is a pathological disease characterized by inflammatory disorders targeting autoantigens. The routine treatment of autoimmune diseases suppresses general immune function to regulate uncontrolled inflammation. The current targeted immunotherapy suppresses the main pro-inflammatory signaling pathways by blocking inflammatory cytokines, cell surface molecules, and intracellular kinases. As key participants in innate immunity, macrophages and dendritic cells (DCs) are crucial for Ag presentation and pro-inflammatory cytokine production, such as TNF and IL-1 β、 IL-6, IL-23, B cell activating factor (BAFF), and the proliferation-inducing ligand (APRIL, also known as TNFSF13A).

MCE designs a unique collection of 461 autoimmune disease-related compounds, covering multiple targets and subtypes, such as TNF Receptor, IFNAR, JAK, Btk, TLR, IL-6, IL-17, IL-23, etc. It is a useful tool for screening autoimmune disease drugs.

Cat. No.	Product Name	Target	Research Area

HY-P990070

Zigakibart BION-1301	TNF Receptor	Inflammation/Immunology
Zigakibart (BION-1301) is an IgG4-kappa, anti-TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256) humanized monoclonal antibody. Zigakibart shows anti-inflammatory activity .

HY-P99893

Rozibafusp alfa

AMG-570
Inhibitory Antibodies Others

Rozibafusp alfa is an IgG2-κ antibody targeting ICOSLG and a TNFSF13B fusion protein .

Rozibafusp alfa AMG-570	Inhibitory Antibodies	Others
Rozibafusp alfa is an IgG2-κ antibody targeting ICOSLG and a TNFSF13B fusion protein .

Species:	Human (12) Rhesus Macaque (1) Mouse (4) Cynomolgus (3) Canine (1)
Tag:	His (12) SUMO (1) Tag Free (2) Avi (6) Flag (6) Fc (7)
Source:	HEK293 (15) CHO (1) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P77564

	*APRIL/TNFSF13* Protein, Cynomolgus (HEK293, His-Flag-Avi)** CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik	Cynomolgus	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Cynomolgus (HEK293, His-Flag-Avi) is produced by HEK293 cells (K112-L250) with N-terminal His-, Avi-, and Flag-tags.

HY-P70733

	*APRIL/TNFSF13* Trimer Protein, Human (HEK293, Flag-His)** Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13	Human	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Human APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Human (HEK293, Flag-His) is produced by HEK293 cells (K112-L250) with N-terminal His- and Flag-tags.

HY-P700016AF

	*Animal-Free APRIL/TNFSF13* Protein, Human (His)** TNFSF13; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2	Human	E. coli
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Human APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. Animal-Free APRIL/TNFSF13 Protein, Human (His) is produced by E. coli (A105-L250) with C-terminal His-tag.

HY-P700661

	*APRIL/TNFSF13* Protein, Human (Biotinylated, HEK293, Flag, His-Avi)** CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik	Human	HEK293
	APRIL/TNFSF13 is a TNF superfamily cytokine that affects tumor cell growth by binding to TNFRSF13B/TACI and TNFRSF17/BCMA receptors. Its homotrimeric structure highlights a potential role in oncogenic processes and immune functions involving monocytes and macrophages. APRIL/TNFSF13 Protein, Human (Biotinylated, HEK293, Flag, His-Avi) is the recombinant human-derived APRIL/TNFSF13 protein, expressed by HEK293 , with N-Flag, C-Avi, N-His labeled tag. The total length of APRIL/TNFSF13 Protein, Human (Biotinylated, HEK293, Flag, His-Avi) is 139 a.a., with molecular weight of 55-65 kDa.

HY-P7320

	*APRIL/TNFSF13* Protein, Mouse** rMuApril/TNFSF13; TNFSF 13; TNFSF-13; CD256	Mouse	E. coli
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Mouse APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Mouse is produced by E. coli (R50-L241) with length of 192 amino acids.

HY-P7538

	*APRIL/TNFSF13* Protein, Mouse (HEK293, Fc)** rMuAPRIL/TNFSF13, N-Fc; CD256; TALL2; APRIL; TNFSF13	Mouse	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Mouse APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Mouse (HEK293, Fc) is produced by HEK293 cells (A96-K240) with N-terminal Fc-tag.

HY-P72442

	*BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc)* TNF superfamily member 13b; TNFSF13B; TNLG7A	Rhesus Macaque	HEK293
	The BAFF/TNFSF13B protein is a member of the tetraspanin (TM4SF) family and is actively involved in a variety of cellular processes. BAFF/TNFSF13B is a component of the tetraspanin superfamily and is critical for cell adhesion, migration, and signaling events. BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc) is 152 a.a., with molecular weight of 45-55 kDa.

HY-P700017AF

	*Animal-Free BAFF/TNFSF13B Protein, Human (His)* TNFSF13B; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; TNLG7A; ZTNF4	Human	E. coli
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. Animal-Free BAFF/TNFSF13B Protein, Human (His) is the recombinant human-derived animal-FreeBAFF/TNFSF13B protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free BAFF/TNFSF13B Protein, Human (His) is 152 a.a., with molecular weight of ~17.98 kDa.

HY-P700531

	*BAFF/TNFSF13B Protein, Human (His-SUMO)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	E. coli
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (His-SUMO) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of BAFF/TNFSF13B Protein, Human (His-SUMO) is 218 a.a., with molecular weight of 39.7 kDa.

HY-P77571

	*BAFF/TNFSF13B Protein, Cynomolgus (HEK293, His-Avi)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Cynomolgus	HEK293
	BAFF/TNFSF13B protein is a member of the TNF family and regulates immune responses and cell survival. It is also known as B cell activating factor, which plays a vital role in the development, activation and survival of B cells by binding to receptors such as BAFF-R. BAFF/TNFSF13B Protein, Cynomolgus (HEK293, His-Avi) is the recombinant cynomolgus-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of BAFF/TNFSF13B Protein, Cynomolgus (HEK293, His-Avi) is 145 a.a., with molecular weight of 55-60 kDa.

HY-P78384

	*BAFF/TNFSF13B Protein, Human (HEK293, His-Flag)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (HEK293, His-Flag) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Flag labeled tag. The total length of BAFF/TNFSF13B Protein, Human (HEK293, His-Flag) is 145 a.a., with molecular weight of 53-60 kDa.

HY-P78385

	*BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-hFc, N-Flag labeled tag. The total length of BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag) is 145 a.a., with molecular weight of ~74.9 kDa.

HY-P78066

	*BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, His-Avi)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, His-Avi) is 145 a.a., with molecular weight of 55-68 kDa.

HY-P700459

	*BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with C-Avi, N-hFc labeled tag. The total length of BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi) is 152 a.a., with molecular weight of 46.2 kDa.

HY-P77572

	*BAFF/TNFSF13B Protein, Cynomolgus (Biotinylated, HEK293, His-Flag-Avi)* BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Cynomolgus	HEK293
	BAFF/TNFSF13B protein is a member of the TNF family and regulates immune responses and cell survival. It is also known as B cell activating factor, which plays a vital role in the development, activation and survival of B cells by binding to receptors such as BAFF-R. BAFF/TNFSF13B Protein, Cynomolgus (Biotinylated, HEK293, His-Flag-Avi) is the recombinant cynomolgus-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi, N-Flag labeled tag. The total length of BAFF/TNFSF13B Protein, Cynomolgus (Biotinylated, HEK293, His-Flag-Avi) is 145 a.a., with molecular weight of 55-60 kDa.

HY-P7003

	*BAFF/TNFSF13B Protein, Human (CHO)* 1 Publications Verification rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20	Human	CHO
	BAFF/TNFSF13B Protein, Human (CHO) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.

HY-P75589

	*BAFF/TNFSF13B Protein, Canine (HEK293, Fc)* Tumor necrosis factor ligand superfamily member 13B; BAFF; TALL-1	Canine	HEK293
	BAFF/TNFSF13B Protein, part of the TNF family, is crucial in immune response and cell survival regulation. Also known as B-cell activating factor, it plays a vital role in B-cell development, activation, and survival by binding to receptors like BAFF-R. This interaction promotes B-cell proliferation, antibody production, and the maintenance of mature B cells. Essential for immune system development and function, dysregulated BAFF/TNFSF13B signaling is linked to autoimmune diseases and B-cell malignancies, making it a potential therapeutic target. BAFF/TNFSF13B Protein, Canine (HEK293, Fc) is the recombinant canine-derived BAFF/TNFSF13B protein, expressed by HEK293, with N-hFc labeled tag. The total length of BAFF/TNFSF13B Protein, Canine (HEK293, Fc) is 150 a.a., with molecular weight of ~45.5 kDa.

HY-P70428

	*BAFF/TNFSF13B Protein, Human (HEK293, His)* Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Human	HEK293
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury. Human BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Human (HEK293, His) is the extracullar part of BAFF protein (A134-L285), produced in HEK293 cells with N-terminal 6*His-tag.

HY-P70730

	*BAFF/TNFSF13B Protein, Human (HEK293, Fc)* Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Human	HEK293
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury . Human BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Human (HEK293, Fc) is the extracullar part of BAFF protein (A134-L285), produced in HEK293 cells with N-terminal hFc-tag.

HY-P70816

	*BAFF/TNFSF13B Protein, Mouse (HEK293, Fc)* Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Mouse	HEK293
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury . Mouse BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Mouse (HEK293, Fc) is the extracullar part of BAFF protein (A127-L309), produced in HEK293 cells with N-terminal mFc-tag.

HY-P700161AF

	*Animal-Free BAFF/TNFSF13B Protein, Mouse (His)* Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Mouse	E. coli
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury . Mouse BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. Animal-Free BAFF/TNFSF13B Protein, Mouse (His) is the extracullar part of BAFF protein (A127-L309), produced in HEK293 cells with C-terminal His-tag.


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HY-P82513

APRIL Antibody (YA2258)

APRIL; CD256; TALL2; TNFSF13; TRDL1; ZTNF2
WB, ICC/IF Human, Mouse, Rat

HY-P81765

BAFF Antibody (YA1510) TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD257	FC, ELISA	Human

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