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Results for "

anti-allergic effect

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Peptides

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108259
    HQL-79

    		PGE synthase Inflammation/Immunology
    HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
    HQL-79
  • HY-112390A
    Syk Inhibitor II
    2 Publications Verification

    		 Syk 5-HT Receptor Inflammation/Immunology
    Syk Inhibitor II is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II shows less potent against other kinases and has anti-allergic effect .
    Syk Inhibitor II
  • HY-W015515
    L-Citronellol

    (S)-3,7-Dimethyloct-6-en-1-ol

    		 Environmental Pollutants TNF Receptor Beta-secretase γ-secretase ERK Cholinesterase (ChE) Neurological Disease Inflammation/Immunology
    L-Citronellol ((S)-3,7-Dimethyloct-6-en-1-ol) is a natural product with anti-allergic and neuroprotective effects. L-Citronellol inhibits mast cell activation and the release of inflammatory factors by inhibiting the ERK pathway. L-Citronellol inhibits BACE1/PSEN1 and AChE, reduces TNF-α expression and lipid peroxidation, demonstrating the potential of multi-target anti-Alzheimer's disease (AD) .
    L-Citronellol
  • HY-137941
    Roxatidine

    		Histamine Receptor Caspase NF-κB p38 MAPK Inflammation/Immunology
    Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is an orally active histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect. Roxatidine is promising for research of gastric and duodenal ulcers .
    Roxatidine
  • HY-N15663
    (-)-Epigallocatechin-3-O-(4-O-methyl)gallate

    EGCG4′′Me

    		 Drug Derivative Inflammation/Immunology
    (-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can be used for the researches of immunology and inflammation, such as type I allergic .
    (-)-Epigallocatechin-3-O-(4-O-methyl)gallate
  • HY-112390
    Syk Inhibitor II dihydrochloride

    		5-HT Receptor Syk Inflammation/Immunology
    Syk Inhibitor II dihydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride shows less potent against other kinases and has anti-allergic effect .
    Syk Inhibitor II dihydrochloride
  • HY-112390C
    Syk Inhibitor II hydrochloride

    		5-HT Receptor Syk Inflammation/Immunology
    Syk Inhibitor II hydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II hydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II hydrochloride shows less potent against other kinases and has anti-allergic effect .
    Syk Inhibitor II hydrochloride
  • HY-112390B
    Syk Inhibitor II dihydrochloride dihydrate

    		Syk 5-HT Receptor Inflammation/Immunology
    Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect .
    Syk Inhibitor II dihydrochloride dihydrate
  • HY-137941R
    Roxatidine (Standard)

    		Reference Standards Histamine Receptor Inflammation/Immunology
    Roxatidine (Standard) is the analytical standard of Roxatidine. This product is intended for research and analytical applications. Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect .
    Roxatidine (Standard)
  • HY-N10279
    Gymconopin C

    		Others Infection
    Gymconopin C shows an antiallergic effect on ear passive cutaneous anaphylaxis reactions in mice.
    Gymconopin C
  • HY-N10821A
    Blestriarene A

    (-)-Blestriarene A

    		 Others Inflammation/Immunology
    Blestriarene A ((-)-Blestriarene A) is a active product that can beextracts from the tubers of Gymnadenia conopsea. Blestriarene A shows an antiallergic effect .
    Blestriarene A
  • HY-163061
    Quinotolast

    		Histamine Receptor Inflammation/Immunology
    Quinotolast is an orally active antiallergic agent. Quinotolast inhibits histamine release from rat peritoneal cells. Quinotolast inhibits cutaneous cromoglycate in guinea pig model. Quinotolast has inhibitory effect on histamine and peptide leukotrienes release from guinea pig lung fragments and mouse cultured mast cells. Quinotolast can be studied in allergy-related research .
    Quinotolast
  • HY-124185
    LC 6

    		Others Others
    LC 6 is an anti-allergic compound that has the activity of inhibiting passive cutaneous allergic reactions in rats. Its half effective dose (ED50) is 35 mg/kg body weight. Oral administration is effective and long-lasting, and the effect is obviously dose-dependent. Its long-term binding to mast cells makes it a valuable tool for studying allergic reaction receptors.
    LC 6
  • HY-108259R
    HQL-79 (Standard)

    		Reference Standards PGE synthase Inflammation/Immunology
    HQL-79 (Standard) is the analytical standard of HQL-79 (HY-108259). This product is intended for research and analytical applications. HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
    HQL-79 (Standard)
  • HY-116481
    Selenotifen

    BN 52256

    		 Platelet-activating Factor Receptor (PAFR) Cardiovascular Disease Inflammation/Immunology
    Selenotifen (BN 52256) is an antiallergic agent. Selenotifen is a highly potent antagonist to PAF receptors. Selenotifen exhibits a statistically significant antiarrhythmic effect .
    Selenotifen
  • HY-N18182
    Mudanpioside E

    		Glycosidase Inflammation/Immunology
    Mudanpioside E is an orally effective paeoniflorin-type monoterpene glycoside antiallergic agent, with an IC50 of 40.34 μM against IgE-mediated β-hexosaminidase release. Mudanpioside E reverses the inhibitory effect of the modified Xiaoqinglong Decoction extract (paeonia root component removed) on passive cutaneous anaphylaxis in mice. Mudanpioside E itself shows no activity against passive cutaneous anaphylaxis. Mudanpioside E can be used in research related to allergic diseases .
    Mudanpioside E

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