Gymconopin C
Gymconopin C shows an antiallergic effect on ear passive cutaneous anaphylaxis reactions in mice.
For research use only. We do not sell to patients.
- CAS No.: 844493-85-2
- Formula: C30H26O6
- Molecular Weight:482.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
12 μM
Compound: 24
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Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
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[PMID: 31415170] |
| Neutrophil | IC50 |
0.5 μM
Compound: 25
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Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
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[PMID: 27525452] |
| Neutrophil | IC50 |
1.5 μM
Compound: 25
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Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
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[PMID: 27525452] |
Chemical Information
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CAS No. 844493-85-2
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Molecular Weight 482.52
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Formula C30H26O6
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SMILES
OC1=CC=C2C(CCC3=C(C4=C(O)C=C(CCC5=CC(O)=CC(OC)=C65)C6=C4)C(O)=CC(OC)=C23)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gymconopin C Related Classifications
HY-N10279 Related Classifications
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