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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
bacterial invasion
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "bacterial invasion" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: Diazoresorcinol sodium
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1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
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1 Cited Publications
Cat. No.: HY-P1108A
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Synonyms: Diazoresorcinol sodium, indicator
Cat. No.: HY-N2947
CAS No.: 114567-34-9
Category:
Natural Products other families Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-B0614A
CAS No.: 13009-99-9
Mafenide Acetate is a potent sulfonamide antimicrobial agent. Mafenide Acetate exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide Acetate also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide Acetate can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
Mafenide hydrochloride is a potent sulfonamide antimicrobial agent. Mafenide hydrochloride exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide hydrochloride also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide hydrochloride can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
Cat. No.: HY-158082B
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 40000
Mafenide is a potent sulfonamide antimicrobial agent. Mafenide exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
Cat. No.: HY-DY1051
CAS No.: 62758-13-8
Solvent and Concentration: Sterile water: 10 mM
Cat. No.: HY-P5681
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Cat. No.: HY-135562
CAS No.: 38462-04-3
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Ascofuranone is an orally active inhibitor of Trypanosoma brucei brucei (TAO) with a Ki value of 2.38 nM. Ascofuranone inhibits IGF-1-induced cancer cell migration, invasion, motility and actin cytoskeleton formation, and exerts anti-tumor effects. Ascofuranone can be used in research related to tumor metastasis, African trypanosomiasis, bacterial infections, lung cancer and hepatocellular carcinoma .
Cat. No.: HY-D1460
CAS No.: 134869-04-8
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N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)) is a rate-limiting enzyme in bacteria metabolism that catalyzes the reversible aldol cleavage of sialic acid, and it regulates the overall metabolism of the bacterial sialic acid catabolic pathway. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation reaction of pyruvate and N-acetyl-d-mannosamine (ManNAc) to produce sialic acid N-acetylneuraminic acid (Neu5Ac). The protein expression of N-Acetylneuraminate lyase is downregulated at the translational level under the regulation of methyl methanesulfonate, and this change significantly impairs the adhesion and invasion abilities of bacteria to eukaryotic cells. N-Acetylneuraminate lyase is a key virulence-related protein in various pathogenic bacteria and is considered an antibiotic drug target. N-Acetylneuraminate lyase (CgNal) can be used in studies of invasive (extraintestinal) infectious diseases, Crohn's disease, and methicillin-resistant Staphylococcus aureus infections .
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Cardiovascular Disease Infection Neurological Disease Cancer
Lubeluzole dihydrochloride is the dihydrochloride salt of Lubeluzole (HY-105084). Lubeluzole dihydrochloride is the S-isomer of benzothiazole derivative. Lubeluzole dihydrochloride can inhibit glutamate release, glutamate-activated NO synthesis and block voltage-gated Sodium Channel and Calcium Channel. Lubeluzole dihydrochloride exhibits anti-ischemic and neuroprotective effects. Lubeluzole dihydrochloride also shows anti-bacterial and anti-diarrheal potential. Lubeluzole dihydrochloride can inhibit cardiac sodium channel and prolong cardiac action potential. Lubeluzole dihydrochloride can inhibit cancer cells proliferation and invasion and shows chemosensitizing effect. Lubeluzole dihydrochloride can be used for the researches of cancer, infection, neurological and cardiovascular disease such as stroke, infectious diarrhea and ovarian .
Cat. No.: HY-135477
CAS No.: 204130-08-5
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RWJ-60475 is a cell-permeable tyrosine phosphatase inhibitor with an IC50 of 3.3 μM. RWJ-60475, by inhibiting the activity of CD45/CD148 phosphatase, interferes with the phagocytic function of macrophages, thereby blocking the invasion of Legionella pneumophila into host cells and the transport of effector proteins. RWJ-60475 significantly reduces the uptake of bacterial particles by macrophages. RWJ-60475 can be used in the research of anti-infection targeting host factors .
Cat. No.: HY-105084
CAS No.: 144665-07-6
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Research Areas:
Infection Cardiovascular Disease Neurological Disease Cancer
Lubeluzole is the S-isomer of benzothiazole derivative. Lubeluzole can inhibit glutamate release, glutamate-activated NO synthesis and block voltage-gated Sodium Channel and Calcium Channel. Lubeluzole exhibits anti-ischemic and neuroprotective effects. Lubeluzole also shows anti-bacterial and anti-diarrheal potential. Lubeluzole can inhibit cardiac sodium channel and prolong cardiac action potential. Lubeluzole can inhibit cancer cells proliferation and invasion and shows chemosensitizing effect. Lubeluzole can be used for the researches of cancer, infection, neurological and cardiovascular disease such as stroke, infectious diarrhea and ovarian .
Cat. No.: HY-178912
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Anti-MRSA agent 39 is an orally active ClpX modulator that binds Staphylococcus aureus caseinolytic protease X (SaClpX) with high affinity (Kd = 3.6 μM). Anti-MRSA agent 39 exerts antibacterial effects through temperature-dependent inhibition of cell division. Anti-MRSA agent 39 elicits profound metabolic dysregulation in methicillin-resistant Staphylococcus aureus (MRSA), manifesting as significantly reduced ATP levels, elevated reactive oxygen species (ROS), and decreased NAD+/NADH ratio, and accelerates bacterial lysis rates in MRSA ATCC 33591. Anti-MRSA agent 39 significantly increases the proportion of MRSA cells in the mitotic phase, and the cells exhibit obvious morphological abnormalities. Anti-MRSA agent 39 can be used for the study of invasive MRSA infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
