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Lubeluzole is a neuroprotective anti-ischemic compound. Lubeluzole, but not its (-)-R-isomer, protects against sensorimotor deficits provoked by photochemical stroke in rats. Lubeluzole inhibited glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with an IC50 of 37 nM. Lubeluzole also has the potential for developing a novel class of antibacterial adjuvants endowed with spasmolytic activity.

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Lubeluzole Chemical Structure

Lubeluzole Chemical Structure

CAS No. : 144665-07-6

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Description

Lubeluzole is a neuroprotective anti-ischemic compound. Lubeluzole, but not its (-)-R-isomer, protects against sensorimotor deficits provoked by photochemical stroke in rats. Lubeluzole inhibited glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with an IC50 of 37 nM. Lubeluzole also has the potential for developing a novel class of antibacterial adjuvants endowed with spasmolytic activity[1][2].

Molecular Weight

433.51

Formula

C22H25F2N3O2S

CAS No.
SMILES

CN(C1CCN(CC1)C[C@H](O)COC2=CC(F)=C(C=C2)F)C3=NC4=CC=CC=C4S3

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Room temperature in continental US; may vary elsewhere.

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Lubeluzole Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lubeluzole
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HY-105084
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