Boeravinone B
Based on 1 Customer Validation
Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress.
For research use only. We do not sell to patients.
- Purity: 97.59%
- CAS No.: 114567-34-9
- Formula: C17H12O6
- Molecular Weight:312.27
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Boeravinone B is also active against a methicillin-resistant S. aureus (MRSA) strain, which showed a fourfold reduction in the ciprofloxacin MIC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 114567-34-9
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Appearance Solid
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Molecular Weight 312.27
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Formula C17H12O6
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Color Light yellow to yellow
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SMILES
O=C1C2=C(C(O)OC3=CC=CC=C32)OC4=CC(O)=C(C)C(O)=C14
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (160.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (623 KB)
- English - EN (623 KB)
- Français - FR (623 KB)
- Deutsch - DE (623 KB)
- Norwegian - NO (623 KB)
- Español - ES (623 KB)
- Swedish - SV (623 KB)
- Italian - IT (623 KB)
- Korean - KR (623 KB)
- Portuguese - PT (623 KB)
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Handling Instructions (2659 KB)
References
[1]. Samsher Singh, Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and Intracellular Invasion of Bacteria. Front Microbiol. 2017 Oct 4;8:1868. [Content Brief]
[2]. Shivtej P Biradar, et al. Chebulinic acid and Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress. Mitochondrion. 2019 May;46:236-246. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2024 mL | 16.0118 mL | 32.0236 mL | 80.0589 mL |
| 5 mM | 0.6405 mL | 3.2024 mL | 6.4047 mL | 16.0118 mL | |
| 10 mM | 0.3202 mL | 1.6012 mL | 3.2024 mL | 8.0059 mL | |
| 15 mM | 0.2135 mL | 1.0675 mL | 2.1349 mL | 5.3373 mL | |
| 20 mM | 0.1601 mL | 0.8006 mL | 1.6012 mL | 4.0029 mL | |
| 25 mM | 0.1281 mL | 0.6405 mL | 1.2809 mL | 3.2024 mL | |
| 30 mM | 0.1067 mL | 0.5337 mL | 1.0675 mL | 2.6686 mL | |
| 40 mM | 0.0801 mL | 0.4003 mL | 0.8006 mL | 2.0015 mL | |
| 50 mM | 0.0640 mL | 0.3202 mL | 0.6405 mL | 1.6012 mL | |
| 60 mM | 0.0534 mL | 0.2669 mL | 0.5337 mL | 1.3343 mL | |
| 80 mM | 0.0400 mL | 0.2001 mL | 0.4003 mL | 1.0007 mL | |
| 100 mM | 0.0320 mL | 0.1601 mL | 0.3202 mL | 0.8006 mL |
Boeravinone B Related Classifications
HY-N2947 Related Classifications
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