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phosphoserine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) Calcium Channel (2) Endogenous Metabolite (3) Fluorescent Dye (1) Insulin Receptor (1) Isotope-Labeled Compounds (2) Liposome (3) mGluR (2) Phosphatase (2) PKA (1) Reference Standards (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (4)
Oligonucleotides:	Phospholipids (2)

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Recombinant Proteins

Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141613

*1,2-Dioleoyl-sn-glycero-3-phospho-L-serine* sodium** DOPS-NA	Liposome	Others
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

HY-160955

Z218484536	Phosphatase	Neurological Disease
Z218484536 is a selective and brain-penetrant phosphoserine phosphatase (PSPH) inhibitor. Z218484536 binds to PSPH with a K_d value of approximately 0.23 μM. Z218484536 reduces L-serine and D-serine levels in astrocytes. Z218484536 is able to suppress spontaneous epileptic seizures without causing serious side effects. Z218484536 also shows good anti-epileptic effects in the temporal lobe epilepsy (TLE) model .

HY-15130

DL-O-Phosphoserine	Endogenous Metabolite	Metabolic Disease
DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of serine racemase and phagocytosis. O-phospho-L-serine inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development .

HY-100786

DL-AP3 1 Publications Verification	Endogenous Metabolite mGluR Phosphatase	Neurological Disease Cancer
DL-AP3 is a competitive mGluR1 and mGluR5 antagonist. DL-AP3 is also an inhibitor of phosphoserine phosphatase. DL-AP3 has neuroprotective effect .

HY-145539

1,2-Dipalmitoyl-sn-glycero-3-PS sodium	Liposome	Others
1,2-Dipalmitoyl-sn-glycero-3-PS sodium is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS sodium is used for the preparation of phospholipid bilayers .

HY-108546

L-AP3 3-Phosphono-L-alanine	mGluR	Neurological Disease
L-AP3, metabotropic glutamate receptor (mGluR) antagonist, inhibits *D-phosphoserine* and *L-phosphoserine* with IC₅₀s of 368 μM and 2087 μM, respectively .

HY-15130R

*DL-O-Phosphoserine* (Standard)**	Reference Standards Endogenous Metabolite	Metabolic Disease
Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-P0291

Phosphorylated kemptide [Phospho-Ser5]kemptide	PKA	Others
Phosphorylated kemptide is a phosphoserine-containing Kemptide (HY-P0248) peptide. Phosphorylated kemptide can be used as a substrate for phosphatases .

HY-161478

Phosphoserine/BSA	Biochemical Assay Reagents	Inflammation/Immunology
Phosphoserine/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-165473

Hexadecylphosphoserine	Calcium Channel	Cancer
Hexadecylphosphoserine is a phospholipid molecule that contains a long-chain alkyl (hexadecyl) and a phosphoserine group, giving it a high affinity for the cell membrane. Hexadecylphosphoserine can exert antitumor activity by modulating [Ca ⁺⁺]_i and its related signaling pathways, making it useful for research in the field of breast cancer .

HY-165473A

Hexadecylphosphoserine TFA	Calcium Channel	Cancer
Hexadecylphosphoserine TFA is a phospholipid molecule that contains a long-chain alkyl (hexadecyl) and a phosphoserine group, giving it a high affinity for the cell membrane. Hexadecylphosphoserine TFA can exert antitumor activity by modulating [Ca ⁺⁺]_i and its related signaling pathways, making it useful for research in the field of breast cancer .

HY-P3480

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA	Fluorescent Dye	Others
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .

HY-177192

1,2-Dimyristoyl-sn-glycero-3-phosphoserine DMPS	Biochemical Assay Reagents	Others
1,2-Dimyristoyl-sn-glycero-3-phosphoserine (DMPS) is an anionic, negatively charged phosphatidylserine phospholipid. 1,2-Dimyristoyl-sn-glycero-3-phosphoserine acts as an internal standard for liquid chromatography/mass spectrometry analyses .

HY-178730S

*1,2-Dimyristoyl-sn-glycero-3-phosphoserine-d3 ammonium* DMPS-d3 ammonium	Isotope-Labeled Compounds	Others
1,2-Dimyristoyl-sn-glycero-3-phosphoserine-d₃ ammonium (DMPS-d₃ ammonium) is the deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphoserine ammonium.

HY-183840

PP185	Insulin Receptor	Neurological Disease Cancer
PP185 is a insulin receptor kinase substrate. PP185 undergoes rapid tyrosine phosphorylation, with activity dependent on divalent cations and inhibited by insulin receptor kinase domain antibodies. PP185 can be used for the research of neuroblastoma .

HY-145539A

1,2-Dipalmitoyl-sn-glycero-3-PS	Liposome	Others
1,2-Dipalmitoyl-sn-glycero-3-PS is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS is used for the preparation of phospholipid bilayers .

HY-141613S

*(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium* (2S,8R,19Z)DOPS-d3 ammonium	Isotope-Labeled Compounds	Others
(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d₃ ammonium ((2S,8R,19Z)DOPS-d₃ ammonium) is the deuterium labeled (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium (HY-141613). 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

Cat. No.	Product Name	Type

HY-141613

*1,2-Dioleoyl-sn-glycero-3-phospho-L-serine* sodium** DOPS-NA	Biochemical Assay Reagents
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium

DOPS-NA

Biochemical Assay Reagents

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

HY-145539

1,2-Dipalmitoyl-sn-glycero-3-PS sodium	Biochemical Assay Reagents
1,2-Dipalmitoyl-sn-glycero-3-PS sodium is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS sodium is used for the preparation of phospholipid bilayers .

HY-161478

Phosphoserine/BSA	Biochemical Assay Reagents
Phosphoserine/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

Cat. No.	Product Name	Target	Research Area

HY-P5531

beta-Casein phosphopeptide	Peptides	Others
beta-Casein phosphopeptide is a biological active peptide. (Bovine -Casein, monophosphopeptide (phospho-Serine) can be used for characterization of affinity purified phosphorylated peptides in liquid chromatography and for the analysis or detection of phosphorylated peptides in mass spectrometry.)

HY-P0291

Phosphorylated kemptide [Phospho-Ser5]kemptide	PKA	Others
Phosphorylated kemptide is a phosphoserine-containing Kemptide (HY-P0248) peptide. Phosphorylated kemptide can be used as a substrate for phosphatases .

HY-P3480

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA	Fluorescent Dye	Others
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15130

DL-O-Phosphoserine	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of serine racemase and phagocytosis. O-phospho-L-serine inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development .

HY-100786

DL-AP3 1 Publications Verification	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite mGluR Phosphatase
DL-AP3 is a competitive mGluR1 and mGluR5 antagonist. DL-AP3 is also an inhibitor of phosphoserine phosphatase. DL-AP3 has neuroprotective effect .

HY-15130R

*DL-O-Phosphoserine* (Standard)**	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

Species:	Human (4)
Tag:	His (3) Tag Free (2)
Source:	E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71241

	PSP Protein, Human (His) phosphoserine Phosphatase; PSP; PSPase; L-3-phosphoserine Phosphatase; O-phosphoserine Phosphohydrolase; PSPH	Human	E. coli
	PSP protein catalyzes the final irreversible step in carbohydrate biosynthesis of L-serine through dephosphorylation of O-phospho-L-serine. PSP Protein, Human (His) is the recombinant human-derived PSP protein, expressed by E. coli , with C-6*His labeled tag.

HY-P78999

	PSAT1 Protein, Human (His) phosphoserine aminotransferase; PSAT1; Phosphohydroxythreonine aminotransferase; PSAT; PSA; phosphoserine Aminotransferase 1	Human	E. coli
	The PSAT1 protein plays a central role in cellular metabolism by catalyzing the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and 3-hydroxy-2-oxo-4-phosphonooxybutyrate to phosphohydroxythreonine. These enzyme activities are key steps in the biosynthetic pathway of the essential amino acids serine and threonine. PSAT1 Protein, Human (His) is the recombinant human-derived PSAT1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P701351

	PSAT1 Protein, Human PSAT1; phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT	Human	E. coli
	The PSAT1 protein plays a central role in cellular metabolism by catalyzing the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and 3-hydroxy-2-oxo-4-phosphonooxybutyrate to phosphohydroxythreonine. These enzyme activities are key steps in the biosynthetic pathway of the essential amino acids serine and threonine. PSAT1 Protein, Human is the recombinant human-derived PSAT1 protein, expressed by E. coli , with tag free.

HY-P701352

	PSAT1 Protein, Human (N-His) PSAT1; phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT	Human	E. coli
	The PSAT1 protein plays a central role in cellular metabolism by catalyzing the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and 3-hydroxy-2-oxo-4-phosphonooxybutyrate to phosphohydroxythreonine. These enzyme activities are key steps in the biosynthetic pathway of the essential amino acids serine and threonine. PSAT1 Protein, Human (N-His) is the recombinant human-derived PSAT1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703425

	serB2 Protein, Mycobacterium tuberculosis phosphoserine phosphatase SerB2; O-phosphoserine phosphohydrolase; Protein-serine/threonine phosphatase; 3.1.3.16; serB2; Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); Hydrolase; 3.1.3.3	Others	E. coli
	serB2 Protein, Mycobacterium tuberculosis is the recombinant serB2, expressed by E. coli , with tag Free labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-178730S

*1,2-Dimyristoyl-sn-glycero-3-phosphoserine-d3 ammonium*
1,2-Dimyristoyl-sn-glycero-3-phosphoserine-d₃ ammonium (DMPS-d₃ ammonium) is the deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphoserine ammonium.

HY-141613S

*(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium*
(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d₃ ammonium ((2S,8R,19Z)DOPS-d₃ ammonium) is the deuterium labeled (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium (HY-141613). 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium

(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d₃ ammonium ((2S,8R,19Z)DOPS-d₃ ammonium) is the deuterium labeled (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium (HY-141613). 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

Host:	Mouse (1) Rabbit (1)
Reactivity:	Human (1) Rat (1) Mouse (1) Species independent (1)
Application:	IHC-P (2) ICC/IF (1) IP (2) WB (2) FC (1)
Isotype:	IgG (1)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Phosphorylated (1) Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86064

	Phosphoserine Antibody (YA5756)	WB, IHC-P, ICC/IF, IP	Species independent
	Phosphoserine Antibody (YA5756) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Phosphoserine.

HY-P87041

	Phosphoserine aminotransferase Antibody (YA6734) EC 2.6.1.52 antibody; Endometrial progesterone induced protein antibody; EP; IP : antibody; MGC1460 antibody; NLS2 antibody; Phosphohydroxythreonine aminotransferase antibody; phosphoserine aminotransferase 1 antibody; phosphoserine aminotransferase antibody; PSA antibody; PSAT antibody; EC 2.6.1.52 antibody; Endometrial progesterone induced protein antibody; EP; IP : antibody; MGC1460 antibody; NLS2 antibody; Phosphohydroxythreonine aminotransferase antibody; phosphoserine aminotransferase 1 antibody; phosphoserine aminotransferase antibody; PSA antibody; PSAT antibody; Psat1 antibody; PSATD antibody; SERC_HUMAN antibody;	WB, IHC-P, FC, IP	Human, Mouse, Rat
	Phosphoserine aminotransferase Antibody (YA6734) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phosphoserine aminotransferase.

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Cat. No.	Product Name		Classification

HY-141613

*1,2-Dioleoyl-sn-glycero-3-phospho-L-serine* sodium** DOPS-NA		Phospholipids
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

HY-145539

1,2-Dipalmitoyl-sn-glycero-3-PS sodium		Phospholipids
1,2-Dipalmitoyl-sn-glycero-3-PS sodium is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS sodium is used for the preparation of phospholipid bilayers .

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phosphoserine

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Natural
Products