pα1

By Targets:	Akt (1) Antibiotic (2) Apoptosis (2) Autophagy (2) Bcl-2 Family (1) Biochemical Assay Reagents (2) Calcium Channel (1) Caspase (1) Endogenous Metabolite (4) GABA Receptor (4) Glycosyltransferase (1) HIF/HIF Prolyl-Hydroxylase (5) Isotope-Labeled Compounds (2) MAP3K (1) MDM-2/p53 (3) Microtubule/Tubulin (2) mTOR (1) NF-κB (1) p38 MAPK (2) Parasite (2) PARP (1) PI3K (2) Proteasome (1) Sodium Channel (1)
By Research Areas:	Cancer (7) Infection (2) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (5)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0639

Amifostine 5 Publications Verification WR2721	MDM-2/p53 HIF/HIF Prolyl-Hydroxylase	Cancer
Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and *p53* inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action .

HY-B0639A

Amifostine trihydrate 5 Publications Verification WR2721 trihydrate	MDM-2/p53 HIF/HIF Prolyl-Hydroxylase	Cancer
Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and *p53* inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action .

HY-120823

PF-05381941

MAP3K p38 MAPK Inflammation/Immunology

PF-05381941 is a potent dual inhibitor of TAK1/p38α, with IC₅₀s of 156 and186 nM, respectively .

PF-05381941	MAP3K p38 MAPK	Inflammation/Immunology
PF-05381941 is a potent dual inhibitor of *TAK1/p38α, with IC₅₀*s of 156 and186 nM, respectively .

HY-D1510

4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside	Biochemical Assay Reagents	Others
4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety .

HY-E70047

alpha-1,4-Galactosyltransferase (LgtC) A4GALT	Glycosyltransferase	Metabolic Disease
alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens .

HY-11087

SD 0006 SD-06	p38 MAPK Autophagy	Inflammation/Immunology
SD 0006 (SD-06) is an orally active, selective, ATP-competitive and potent diaryl pyrazole inhibitor of p38α MAP kinase, with an IC₅₀ of 110 nM for p38α .

HY-Y0313S

p-Hydroxybenzaldehyde-d4	Isotope-Labeled Compounds Endogenous Metabolite GABA Receptor	Neurological Disease
p-Hydroxybenzaldehyde-d₄ is the deuterium labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

HY-Y0313S1

p-Hydroxybenzaldehyde-13C	Isotope-Labeled Compounds Endogenous Metabolite GABA Receptor	Neurological Disease
p-Hydroxybenzaldehyde- ¹³C is the ¹³C-labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

HY-Y0313S2

p-Hydroxybenzaldehyde-d5	GABA Receptor Endogenous Metabolite	Neurological Disease
p-Hydroxybenzaldehyde-d₅ is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].

HY-Y0313

p-Hydroxybenzaldehyde	Endogenous Metabolite GABA Receptor	Neurological Disease
p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABA_A receptor of the α₁β₂γ₂S subtype at high concentrations.

HY-N6775

Sonolisib 1 Publications Verification PX-866	PI3K	Cancer
Sonolisib (PX-866), an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC₅₀=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity .

HY-146540

GEM-5	HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53	Cancer
GEM-5 is a gemcitabine-based conjugate containing a *HIF-1α* inhibitor (YC-1) (IC₅₀=30 nM). GEM-5 can significantly down-regulate the expression of *HIF-1α* and up-regulate the expression of tumor suppressor *p53. GEM-5 induces the apoptosis* of A2780 cells and inhibits tumor growth .

HY-N1987

Cucurbitacin IIb
Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α .

HY-B0413S

Fenbendazole-d3 2 Publications Verification	HIF/HIF Prolyl-Hydroxylase Parasite Microtubule/Tubulin Antibiotic	Infection
Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-P0109

(S,S)-Z-FA-FMK
(S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. (S,S)-Z-FA-FMK blocks LPS-induced production of IL-1α and IL-1β. (S,S)-Z-FA-FMK can be used as a negative control for caspase-1 and caspase-2 inhibitors because it lacks an aspartic acid residue at the P1 position .

HY-B0413

Fenbendazole 5 Publications Verification	Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic	Infection
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator *HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis*. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-12286

PI-1840	Proteasome Apoptosis Autophagy Caspase Bcl-2 Family NF-κB PARP	Cancer
PI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC₅₀ value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of proteasome substrates p27, Bax, and IκB-α .

HY-P5869

Kurtoxin	Calcium Channel Sodium Channel	Neurological Disease
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca ²⁺ channel gating inhibitor with a K_d of 15 nM for Cav3.1 (α1G T-type) Ca ²⁺ channel. Kurtoxin can interact with high affinity with native neuronal high-threshold L-type, N-type, and P-type Ca ²⁺ channels in central and peripheral neurons. Kurtoxin also shows cross-reactivity with voltage-gated Na ⁺ channel .

HY-127133

Methylpiperidino pyrazole MPP	Biochemical Assay Reagents
MPP is a highly selective estrogen receptor alpha (ERα) antagonist. MPP reduces the ratio of p-ERα/ERα . https://www.ncbi.nlm.nih.gov/pubmed/29799481 Labouesse MA, et al. Effects of selective estrogen receptor alpha and beta modulators on prepulse inhibition in male mice. Psychopharmacology (Berl). 2015 Aug;232(16):2981-94. https://www.ncbi.nlm.nih.gov/pubmed/25893642

HY-108418

PI3Kδ-IN-15	PI3K	Cancer
PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC₅₀ of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα .

HY-155721

22-(4′-py)-JA 22-(4′-Pyridinecarbonyl) jorunnamycin A	Akt mTOR	Cancer
22-(4′-py)-JA is a semisynthetic derivative of junamycin A (JA) that can be isolated from the Thai blue sponge (Xestospongia sp.). 22-(4′-py)-JA has antimetastatic activity and can inhibit AKT/mTOR/p70S6K signaling. 22-(4′-py)-JA inhibits tumor cell invasion and tube formation in human umbilical vein endothelial cells (HUVEC), downregulates metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF). 22-(4′-py)-JA has potent anticancer activity against non-small cell lung cancer (NSCLC) .

Cat. No.	Product Name	Target	Research Area

HY-P5869

Kurtoxin	Calcium Channel Sodium Channel	Neurological Disease
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca ²⁺ channel gating inhibitor with a K_d of 15 nM for Cav3.1 (α1G T-type) Ca ²⁺ channel. Kurtoxin can interact with high affinity with native neuronal high-threshold L-type, N-type, and P-type Ca ²⁺ channels in central and peripheral neurons. Kurtoxin also shows cross-reactivity with voltage-gated Na ⁺ channel .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0313

p-Hydroxybenzaldehyde	Brachyclados megalanthus Speg. Ketones, Aldehydes, Acids Labiatae Source classification Phenols Plants Endogenous metabolite	Endogenous Metabolite GABA Receptor
p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABA_A receptor of the α₁β₂γ₂S subtype at high concentrations.

Species:	Human (18) Mouse (2)
Tag:	His (16) Tag Free (2) Avi (10) Fc (2)
Source:	HEK293 (14) P. pastoris (4) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P74866

	*IFN-alpha 1/IFNA1 Protein, Mouse (P.pastoris, His)* IFNA1; IFNalpha 1; IFN-alpha 1	Mouse	P. pastoris
	IFN-alpha 1 (IFNA1), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 1 involves in the activation of JAK1 and TYK2 pathway, exerts function by inhibiting viral replication as well as modulating immune response. IFN-alpha 1/IFNA1 Protein, Mouse (P.pastoris, His) is produced in P.pastoris yeast cells with a C-Terminal His-tag.

HY-P7009

	*Collagen Alpha-1(XVIII) Chain/Endostatin Protein, Human (P.pastoris)* rHuEndostatin; Collagen alpha-1(XV) chain	Human	P. pastoris
	Endostatin Protein, Human (P.pastoris) is an endogenous antiangiogenic peptide with multiple antitumor roles through modulation of various receptors in the plasma membrane, such as suppression of angiogenesis and inhibition of tumor-cell migration and invasion.

HY-P71067

	Pentraxin 2/SAP Protein, Human (HEK293, His) Serum Amyloid P-Component; SAP; 9.5S Alpha-1-Glycoprotein; APCS; PTX2	Human	HEK293
	Pentraxin 2/SAP protein, a member of the pentraxin family, promotes innate immunity by recognizing pathogens and promoting their clearance. This soluble pattern recognition receptor is involved in multiple inflammatory processes, including complement activation, opsonization, and immune response regulation. Pentraxin 2/SAP Protein, Human (HEK293, His) is the recombinant human-derived Pentraxin 2/SAP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Pentraxin 2/SAP Protein, Human (HEK293, His) is 204 a.a., with molecular weight of ~30.0 kDa.

HY-P75476

	Alpha 1-Microglobulin Protein, Human (P.pastoris, His) Alpha-1-microglobulin; Protein HC; ITI-LC; Bikunin; AMBP	Human	P. pastoris
	Alpha 1-microglobulin has multiple antioxidant and repairing effects, with reductase, heme-binding and free radical scavenging activities. Within blood vessels, it regulates red blood cell homeostasis and prevents heme- and reactive oxygen species-induced cell damage. Alpha 1-Microglobulin Protein, Human (P.pastoris, His) is the recombinant human-derived Alpha 1-Microglobulin protein, expressed by P. pastoris , with N-His labeled tag. The total length of Alpha 1-Microglobulin Protein, Human (P.pastoris, His) is 143 a.a., with molecular weight of ~17.4 kDa.

HY-P73245

	IFN-alpha 13/IFNA1 Protein, Human (P.pastoris, His) Interferon alpha-1/13; IFN-alpha-1/13; LeIF D; IFNA1; IFNA13	Human	P. pastoris
	IFN-alpha 13 (IFNA1), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 1 involves in the activation of JAK1 and TYK2 pathway, exerts function by inhibiting viral replication as well as modulating immune response. IFN-alpha 13/IFNA1 Protein, Human (P.pastoris, His) is produced in P.pastoris yeast cells with a C-Terminal His-tag.

HY-P71111

	Pentraxin 2/SAP Protein, Mouse (HEK293, His) APCS; PTX2; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P; MGC88159; PTX2serum amyloid P-component; SAP pentaxin-related	Mouse	HEK293
	Pentraxin 2/SAP Protein is a discoid homopentamer composed of five non-covalently bound subunits. Pentraxin 2/SAP Protein, Mouse (HEK293, His) is the recombinant mouse-derived Pentraxin 2/SAP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Pentraxin 2/SAP Protein, Mouse (HEK293, His) is 204 a.a., with molecular weight of 28-32 kDa.

HY-P701771

	RSK1 Protein, Human (Sf9) RPS6KA1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (Sf9) is the recombinant human-derived RSK1 protein, expressed by Sf9 insect cells , with tag free. The total length of RSK1 Protein, Human (Sf9) is 321 a.a., .

HY-P701772

	RSK1 Protein, Human (Sf9, His) RPS6KA1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (Sf9, His) is the recombinant human-derived RSK1 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of RSK1 Protein, Human (Sf9, His) is 321 a.a., .

HY-P72412

	SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) HP Substrate 1; SHPS-1; Bit; Sirp-Alpha-1; Sirp-Alpha-2; Sirp-Alpha-3; p84; CD172a; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP	Human	HEK293
	The SIRP α V4/CD172a protein is an immunoglobulin-like cell surface receptor for CD47 that acts as a docking protein to facilitate the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports the adhesion of cerebellar neurons, promotes neurite growth, and promotes glial cell attachment. SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SIRP alpha/CD172a protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) is 340 a.a., with molecular weight of 50-80 kDa.

HY-P77843

	SIRP alpha V4/CD172a Protein, Human (HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293
	SIRP alpha V4/CD172a Protein, an immunoglobulin-like cell surface receptor for CD47, acts as a docking protein, facilitating the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports adhesion of cerebellar neurons, promotes neurite outgrowth, and facilitates glial cell attachment. Engaging in negative regulation, it modulates receptor tyrosine kinase-coupled responses, phagocytosis, mast cell activation, and dendritic cell activation. CD47 binding prevents dendritic cell maturation, inhibits cytokine production, and limits new world arenavirus infection. SIRP alpha V4/CD172a also participates in ROS signaling, interacting with THBS1 and various proteins. SIRP alpha V4/CD172a Protein, Human (HEK293, His-Avi) is the recombinant human-derived SIRP alpha V4/CD172a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and E33G, L44S, T50S, T52I, R54H mutation. The total length of SIRP alpha V4/CD172a Protein, Human (HEK293, His-Avi) is 340 a.a., with molecular weight of 50-70 kDa.

HY-P77844

	SIRP alpha V4/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293
	SIRP alpha V4/CD172a Protein, an immunoglobulin-like cell surface receptor for CD47, acts as a docking protein, facilitating the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports adhesion of cerebellar neurons, promotes neurite outgrowth, and facilitates glial cell attachment. Engaging in negative regulation, it modulates receptor tyrosine kinase-coupled responses, phagocytosis, mast cell activation, and dendritic cell activation. CD47 binding prevents dendritic cell maturation, inhibits cytokine production, and limits new world arenavirus infection. SIRP alpha V4/CD172a also participates in ROS signaling, interacting with THBS1 and various proteins. SIRP alpha V4/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SIRP alpha V4/CD172a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and E33G, L44S, T50S, T52I, R54H mutation. The total length of SIRP alpha V4/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) is 340 a.a., with molecular weight of 50-70 kDa.

HY-P77846

	SIRP alpha V6/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293
	SIRP alpha V4/CD172a Protein, an immunoglobulin-like cell surface receptor for CD47, acts as a docking protein, facilitating the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports adhesion of cerebellar neurons, promotes neurite outgrowth, and facilitates glial cell attachment. Engaging in negative regulation, it modulates receptor tyrosine kinase-coupled responses, phagocytosis, mast cell activation, and dendritic cell activation. CD47 binding prevents dendritic cell maturation, inhibits cytokine production, and limits new world arenavirus infection. SIRP alpha V4/CD172a also participates in ROS signaling, interacting with THBS1 and various proteins. SIRP alpha V6/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SIRP alpha V6/CD172a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and S105P mutation. The total length of SIRP alpha V6/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) is 340 a.a., with molecular weight of 60-65 kDa.

HY-P77840

	SIRP alpha V2/CD172a Protein, Human (Biotinylated, HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293

HY-P77841

	SIRP alpha V3 Protein, Human (H54L, HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293

HY-P77842

	SIRP alpha V3 Protein, Human (Biotinylated, H54L, HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293

HY-P77845

	SIRP alpha V6/CD172a Protein, Human (HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293
	SIRP alpha V4/CD172a Protein, an immunoglobulin-like cell surface receptor for CD47, acts as a docking protein, facilitating the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports adhesion of cerebellar neurons, promotes neurite outgrowth, and facilitates glial cell attachment. Engaging in negative regulation, it modulates receptor tyrosine kinase-coupled responses, phagocytosis, mast cell activation, and dendritic cell activation. CD47 binding prevents dendritic cell maturation, inhibits cytokine production, and limits new world arenavirus infection. SIRP alpha V4/CD172a also participates in ROS signaling, interacting with THBS1 and various proteins. SIRP alpha V6/CD172a Protein, Human (HEK293, His-Avi) is the recombinant human-derived SIRP alpha V6/CD172a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and S105P mutation. The total length of SIRP alpha V6/CD172a Protein, Human (HEK293, His-Avi) is 340 a.a., with molecular weight of 55-70 kDa.

HY-P78211

	SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, Fc-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293
	The SIRP α V4/CD172a protein is an immunoglobulin-like cell surface receptor for CD47 that acts as a docking protein to facilitate the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports the adhesion of cerebellar neurons, promotes neurite growth, and promotes glial cell attachment. SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived SIRP alpha/CD172a protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, Fc-Avi) is 340 a.a., with molecular weight of 78-90 kDa.

HY-P77836

	SIRP alpha V2/CD172a Protein, Human (339a.a, HEK293, His) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293

HY-P77837

	SIRP alpha V2/CD172a Protein, Human (339a.a, HEK293, Fc) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293

HY-P77847

	SIRP alpha V8/CD172a Protein, Human (S44L, S50T, I52T, H54R, V57A, HEK293, His-Avi) CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3	Human	HEK293

Cat. No.	Product Name	Chemical Structure

HY-Y0313S

p-Hydroxybenzaldehyde-d4
p-Hydroxybenzaldehyde-d₄ is the deuterium labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

HY-B0413S

Fenbendazole-d3

2 Publications Verification

Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-Y0313S1

p-Hydroxybenzaldehyde-13C
p-Hydroxybenzaldehyde- ¹³C is the ¹³C-labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

HY-Y0313S2

p-Hydroxybenzaldehyde-d5
p-Hydroxybenzaldehyde-d₅ is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].

Cat. No.	Product Name	Application	Reactivity

HY-P80848

Phospho-RSK1 p90 (Ser380) Antibody RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, ICC/IF, IP	Human, Rat, Mouse
Phospho-RSK1 p90 (Ser380) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Phospho-RSK1 p90 (Ser380). It can be used for WB, ICC/IF, IP assays with tag free, in the background of Human, Mouse and Rat.

HY-P80886

RSK1 p90 Antibody (YA676) RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IP	Human, Mouse, Monkey
RSK1 p90 Antibody (YA676) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to RSK1 p90 (6B9). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Monkey.

HY-P80849

Phospho-RSK1 p90 (Thr359/Ser363) Antibody RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP	WB, IP	Human, Mouse, Rat
Phospho-RSK1 p90 (Thr359/Ser363) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Phospho-RSK1 p90 (Thr359/Ser363). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.


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