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Pathways Recommended: Vitamin D Related/Nuclear Receptor
Results for "

vitamin D3 metabolite

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

6

Natural
Products

13

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-32343
    Secalciferol
    5+ Cited Publications

    (24R)-24,25-Dihydroxyvitamin D3

    Endogenous Metabolite VD/VDR Metabolic Disease Inflammation/Immunology
    Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC50 value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .
    Secalciferol
  • HY-112023

    9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C

    Endogenous Metabolite Metabolic Disease
    Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D .
    Lumisterol 3 (purity>90%)
  • HY-76814

    VD/VDR Isotope-Labeled Compounds Metabolic Disease
    Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR) .
    Calcitriol-d6
  • HY-13332

    25-hydroxy vitamin D3-d6

    Isotope-Labeled Compounds VD/VDR Metabolic Disease
    Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand .
    Calcifediol-d6
  • HY-15157

    1α, 24, 25-Trihydroxy VD3

    VD/VDR Drug Metabolite Infection
    Calcitetrol (1α, 24, 25-Trihydroxy VD3), a Vitamin D3 (HY-15398) metabolite, is the hormonally active form of vitamin D. Calcitetrol participates in regulation of Treg cells. Calcitetrol can be used for the research of Toxoplasma gondii infection .
    Calcitetrol
  • HY-N10508

    Drug Metabolite VD/VDR Metabolic Disease Cancer
    Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .
    Calcitroic acid
  • HY-10002A

    1α,25-Dihydroxy-3-epi-vitamin-D3

    VD/VDR Others
    (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
    (1S)-Calcitriol
  • HY-77278

    VD/VDR Aryl Hydrocarbon Receptor LXR PPAR Others
    25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor (VDR) and aryl hydrocarbon receptor (AhR), liver X receptor α/β (LXR α/β) and peroxisome proliferator-activated receptor γ (PPARγ), stimulates the expression of CYP24A1 .
    25-Hydroxytachysterol3
  • HY-15830

    25,26-Dihydroxycholecalciferol

    VD/VDR Drug Metabolite Drug Derivative Calcium Channel Metabolic Disease
    25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a dihydroxylated derivative and metabolite of Vitamin D3 (HY-15398). 25,26-Dihydroxyvitamin D3 moderately increases serum calcium levels when the initial serum calcium level is low. 25,26-Dihydroxyvitamin D3 promotes intestinal calcium absorption in vitamin D-deficient rats fed a low-calcium diet. 25,26-Dihydroxyvitamin D3 is applicable to research related to osteomalacia .
    25,26-Dihydroxyvitamin D3
  • HY-13292

    1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol

    VD/VDR Cancer
    Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
    Impurity B of Calcitriol
  • HY-133879

    1α,25-Dihydroxyvitamin D3-26,23-lactone

    Endogenous Metabolite Others Inflammation/Immunology
    Calcitriol lactone (1α,25-Dihydroxyvitamin D3-26,23-lactone) is a metabolite of vitamin D3. Calcitriol lactone is the active form of vitamin D and affects bone health, cell differentiation, immune function .
    Calcitriol lactone
  • HY-32349S

    25-Hydroxy vitamin D2-d3

    Isotope-Labeled Compounds Endogenous Metabolite VD/VDR Metabolic Disease
    Ercalcidiol-d3 is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of Vitamins D2. Ercalcidiol can be used as an indicator of vitamins D status .
    Ercalcidiol-d3
  • HY-10002S1

    1,25-Dihydroxyvitamin D3-d3

    VD/VDR Endogenous Metabolite Cancer
    Calcitriol-d3 is the deuterium labeled Calcitriol . Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist .
    Calcitriol-d3
  • HY-75041

    Biochemical Assay Reagents Metabolic Disease
    Calcitriol Impurities A is an impurity of Calcitriol (HY-10002). Calcitriol is the active metabolite of vitamin D3 and can activate the vitamin D receptor.
    Calcitriol Impurities A
  • HY-10003AR

    Thyroid Hormone Receptor Reference Standards Metabolic Disease
    1α-Hydroxy-3-epi-vitamin D3 (Standard) is the analytical standard of 1α-Hydroxy-3-epi-vitamin D3 (HY-10003A). This product is intended for research and analytical applications. 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .
    1α-Hydroxy-3-epi-vitamin D3 (Standard)
  • HY-10003A

    Thyroid Hormone Receptor Metabolic Disease
    1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .
    1α-Hydroxy-3-epi-vitamin D3
  • HY-142140S

    Isotope-Labeled Compounds Others
    3-epi-25-Hydroxy Vitamin D3-d6 is the deuterium labeled 3-epi-25-Hydroxy Vitamin D3 (HY-142140) . 3-epi-25-Hydroxy Vitamin D3 is the vitamin D metabolite, while vitamin D metabolism highly dependent on macrophage polarization. The C3-epimerase pathway for vitamin D is active in macrophages .
    3-epi-25-Hydroxy Vitamin D3-d6
  • HY-77274

    VD/VDR Metabolic Disease
    Calcitriol Impurities D is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
    Calcitriol Impurities D
  • HY-13293

    VD/VDR Cancer
    Impurity C of Calcitriol is the impurity of Calcitriol (HY-10002). Calcitriol is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
    Impurity C of Calcitriol
  • HY-32350S

    1α,25-Dihydroxy vitamin D2-13C,d3

    Isotope-Labeled Compounds VD/VDR Drug Metabolite Endogenous Metabolite Metabolic Disease
    Ercalcitriol- 13C,d3 is the 13C- and deuterium labeled Ercalcitriol. Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.
    Ercalcitriol-13C,d3
  • HY-10002B

    (1R,5Z)-1,25-Dihydroxyvitamin D3

    VD/VDR Cancer
    (1R,5Z)-Calcitriol ((1R,5Z)-1,25-Dihydroxyvitamin D3) is a Calcitriol (HY-10002) isomer. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist .
    (1R,5Z)-Calcitriol
  • HY-W744265

    N-Acetyl-4-benzoquinone Imine-d3

    Isotope-Labeled Compounds Drug Metabolite Endogenous Metabolite Metabolic Disease
    NAPQI-d3 (N-Acetyl-4-benzoquinone Imine-d3) is the deuterium labeled NAPQI (HY-W017464). NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .
    NAPQI-d3
  • HY-14649S5

    vitamin A acid-d3; all-trans-Retinoic acid-d3; ATRA-d3

    Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy Cancer
    Retinoic acid-d3 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .
    Retinoic acid-d3
  • HY-14649S6

    vitamin A acid-d3-1; all-trans-Retinoic acid-d3-1; ATRA-d3-1

    Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy Metabolic Disease Cancer
    Retinoic acid-d3-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .
    Retinoic acid-d3-1
  • HY-159201

    Calcium Channel Metabolic Disease
    24-Oxo-25-hydroxyvitamin D3 is a vitamin D3 metabolite and an intermediate in the renal mitochondrial side-chain oxidation pathway. 24-Oxo-25-hydroxyvitamin D3 enhances intestinal calcium transport in rats . 24-Oxo-25-hydroxyvitamin D3 can be used in studies related to X-linked hypophosphatemic rickets .
    24-Oxo-25-hydroxyvitamin D3
  • HY-18646

    24-Oxo-23,25-dihydroxyvitamin D3

    Endogenous Metabolite Metabolic Disease
    23,25-Dihydroxy-24-oxovitamin D3 is a major metabolite of 24(R),25-Dihydroxyvitamin D3. 23,25-Dihydroxy-24-oxovitamin D3 can be used for the research of metabolic diseases .
    23,25-Dihydroxy-24-oxovitamin D3
  • HY-10002AS

    1α,25-Dihydroxy-3-epi-vitamin D3-d3

    Isotope-Labeled Compounds VD/VDR Others
    (1S)-Calcitriol-d3 (1α,25-Dihydroxy-3-epi-vitamin D3-d3) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
    (1S)-Calcitriol-d3
  • HY-10002S2

    1,25-Dihydroxyvitamin D3-d9

    Isotope-Labeled Compounds VD/VDR Drug Metabolite Endogenous Metabolite Cancer
    Calcitriol-d9 (1,25-Dihydroxyvitamin D3-d9) is the deuterium labeled Calcitriol (HY-10002). Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
    Calcitriol-d9
  • HY-10002AS2

    1α,25-Dihydroxy-3-epi-vitamin D3-d6

    Isotope-Labeled Compounds VD/VDR Others
    (1S)-Calcitriol-d6 (1α,25-Dihydroxy-3-epi-vitamin D3-d6) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
    (1S)-Calcitriol-d6
  • HY-10002AR

    1α,25-Dihydroxy-3-epi-vitamin-D3 (Standard)

    Reference Standards VD/VDR Others
    (1S)-Calcitriol (Standard) is the analytical standard of (1S)-Calcitriol (HY-10002A). This product is intended for research and analytical applications. (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
    (1S)-Calcitriol (Standard)
  • HY-N10508S

    Isotope-Labeled Compounds VD/VDR Drug Metabolite Metabolic Disease Cancer
    Calcitroic acid- 13C is the 13C-labeled Calcitroic acid (HY-N10508). Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .
    Calcitroic acid-13C

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