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Cat. No.: HY-159201

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24-Oxo-25-hydroxyvitamin D3

24-Oxo-25-hydroxyvitamin D3 is a vitamin D3 metabolite and an intermediate in the renal mitochondrial side-chain oxidation pathway. 24-Oxo-25-hydroxyvitamin D3 enhances intestinal calcium transport in rats. 24-Oxo-25-hydroxyvitamin D3 can be used in studies related to X-linked hypophosphatemic rickets.

For research use only. We do not sell to patients.

CAS No.: 74886-61-6
Formula: C₂₇H₄₂O₃
Molecular Weight:414.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

24-Oxo-25-hydroxyvitamin D3 Chemical Structure

CAS No.: 74886-61-6

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- In Vitro
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Biological Activity

Description

All Calcium Channel Isoforms :

In Vitro

24-Oxo-25-hydroxyvitamin D3 is an intermediate metabolite produced via the side-chain oxidation pathway of 25-OH-D₃ in renal mitochondrial fractions of normal mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 74886-61-6
Molecular Weight 414.63
Formula C₂₇H₄₂O₃
SMILES

C[C@@]12[C@](\C(=C\C=C\3/C(=C)CC[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CCC(C(C)(C)O)=O)C)[H])[H]
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Animals
chicken kidney homogenates
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jones G, et al. Side-chain oxidation of vitamin D3 in mouse kidney mitochondria: effect of the Hyp mutation and 1,25-dihydroxyvitamin D3 treatment. Biochem Cell Biol. 1987;65(10):853-859. [Content Brief]

[2]. Y Takasaki, et al. Isolation and identification of 25-hydroxy-24-oxocholecalciferol: A metabolite of 25-hydroxycholecalciferol. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Pages 177-181.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
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24-Oxo-25-hydroxyvitamin D3

All Calcium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

24-Oxo-25-hydroxyvitamin D3 Related Classifications

HY-159201 Related Classifications