Calcitetrol
Based on 1 Customer Validation
Calcitetrol (1α, 24, 25-Trihydroxy VD3), a Vitamin D3 (HY-15398) metabolite, is the hormonally active form of vitamin D. Calcitetrol participates in regulation of Treg cells. Calcitetrol can be used for the research of Toxoplasma gondii infection.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 72203-93-1
- Formula: C27H44O4
- Molecular Weight:432.64
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Calcitetrol undergoes further metabolism by recombinant rat kidney calcidiol 24-hydroxylase (P450cc24) into 24-oxo-1,25-dihydroxyvitamin D3, which converts to 24-oxo-1,23,25-trihydroxyvitamin D3[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 72203-93-1
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Appearance Solid
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Molecular Weight 432.64
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Formula C27H44O4
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Color White to off-white
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SMILES
O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCC(O)C(C)(O)C)C)([H])[C@]3(C)CCC\2
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Synonyms
1α, 24, 25-Trihydroxy VD3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (231.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Ma J, et al. Metabolomic signature of mouse cerebral cortex following Toxoplasma gondii infection. Parasit Vectors. 2019;12(1):373. Published 2019 Jul 29. [Content Brief]
[2]. Akiyoshi-Shibata M, et al. Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. A study with the mature enzyme expressed in Escherichia coli. Eur J Biochem. 1994;224(2):335-343. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3114 mL | 11.5570 mL | 23.1139 mL | 57.7848 mL |
| 5 mM | 0.4623 mL | 2.3114 mL | 4.6228 mL | 11.5570 mL | |
| 10 mM | 0.2311 mL | 1.1557 mL | 2.3114 mL | 5.7785 mL | |
| 15 mM | 0.1541 mL | 0.7705 mL | 1.5409 mL | 3.8523 mL | |
| 20 mM | 0.1156 mL | 0.5778 mL | 1.1557 mL | 2.8892 mL | |
| 25 mM | 0.0925 mL | 0.4623 mL | 0.9246 mL | 2.3114 mL | |
| 30 mM | 0.0770 mL | 0.3852 mL | 0.7705 mL | 1.9262 mL | |
| 40 mM | 0.0578 mL | 0.2889 mL | 0.5778 mL | 1.4446 mL | |
| 50 mM | 0.0462 mL | 0.2311 mL | 0.4623 mL | 1.1557 mL | |
| 60 mM | 0.0385 mL | 0.1926 mL | 0.3852 mL | 0.9631 mL | |
| 80 mM | 0.0289 mL | 0.1445 mL | 0.2889 mL | 0.7223 mL | |
| 100 mM | 0.0231 mL | 0.1156 mL | 0.2311 mL | 0.5778 mL |
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