1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Lumisterol 3 (>90%)

Lumisterol 3 (>90%) (Synonyms: 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C)

Cat. No.: HY-112023 Purity: 97.39%
Handling Instructions

Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D.

For research use only. We do not sell to patients.

Lumisterol 3 (>90%) Chemical Structure

Lumisterol 3 (>90%) Chemical Structure

CAS No. : 5226-01-7

Size Price Stock Quantity
1 mg USD 195 In-stock
Estimated Time of Arrival: December 31
5 mg USD 720 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1250 In-stock
Estimated Time of Arrival: December 31
25 mg USD 2550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 4200 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

Lumisterol 3 (L3) (1-100 nM, 24 h) significantly reduces UVB-induced cellular oxidant formation in a dose-dependent manner and inhibits the proliferation of UVB-irradiated keratinocytes[2].
Lumisterol 3 (L3) (100 nM, 24 h) promotes repair of cellular DNA damage induced by UVB irradiation and increases the nuclear/cytosolic Nrf2 ratio and nuclear p53 expression level in UVB-irradiated cells[2].
Lumisterol 3 (L3) (100 nM, 3 h) significantly enhances the expression levels of Nrf2-regulated antioxidant proteins, including catalase and HO-1 in UVB-irradiated cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

384.64

Formula

C27H44O

CAS No.
SMILES
Shipping

Shipping with dry ice.

Storage

-80°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (5.20 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 97.39%

References
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Lumisterol 3 (>90%)
Cat. No.:
HY-112023
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