1. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  2. Endogenous Metabolite VD/VDR
  3. Secalciferol

Secalciferol  (Synonyms: (24R)-24,25-Dihydroxyvitamin D3)

Cat. No.: HY-32343 Purity: 99.49%
COA Handling Instructions

Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system.

For research use only. We do not sell to patients.

Secalciferol Chemical Structure

Secalciferol Chemical Structure

CAS No. : 55721-11-4

Size Price Stock Quantity
1 mg USD 600 In-stock
5 mg USD 2640 In-stock
10 mg   Get quote  
50 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Secalciferol:

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Description

Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

416.64

Formula

C27H44O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=C(CC1)/C(C[C@H]1O)=C\C=C2[C@@]3([H])[C@@](CCC\2)(C)[C@@H]([C@H](C)CC[C@@H](O)C(C)(C)O)CC3

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (240.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : 50 mg/mL (120.01 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4002 mL 12.0008 mL 24.0015 mL
5 mM 0.4800 mL 2.4002 mL 4.8003 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.49%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO 1 mM 2.4002 mL 12.0008 mL 24.0015 mL 60.0038 mL
5 mM 0.4800 mL 2.4002 mL 4.8003 mL 12.0008 mL
10 mM 0.2400 mL 1.2001 mL 2.4002 mL 6.0004 mL
15 mM 0.1600 mL 0.8001 mL 1.6001 mL 4.0003 mL
20 mM 0.1200 mL 0.6000 mL 1.2001 mL 3.0002 mL
25 mM 0.0960 mL 0.4800 mL 0.9601 mL 2.4002 mL
30 mM 0.0800 mL 0.4000 mL 0.8001 mL 2.0001 mL
40 mM 0.0600 mL 0.3000 mL 0.6000 mL 1.5001 mL
50 mM 0.0480 mL 0.2400 mL 0.4800 mL 1.2001 mL
60 mM 0.0400 mL 0.2000 mL 0.4000 mL 1.0001 mL
80 mM 0.0300 mL 0.1500 mL 0.3000 mL 0.7500 mL
100 mM 0.0240 mL 0.1200 mL 0.2400 mL 0.6000 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Secalciferol
Cat. No.:
HY-32343
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