1. Vitamin D Related
    Metabolic Enzyme/Protease
  2. VD/VDR
    Endogenous Metabolite
  3. 25,26-Dihydroxyvitamin D3

25,26-Dihydroxyvitamin D3 (Synonyms: 25,26-Dihydroxycholecalciferol)

Cat. No.: HY-15830 Purity: 98.08%
Handling Instructions

25,26-Dihydroxyvitamin D3(25,26-dihydroxycholecalciferol) is a metabolite of vitamin D3 with intestinal calcium transport activity.

For research use only. We do not sell to patients.

25,26-Dihydroxyvitamin D3 Chemical Structure

25,26-Dihydroxyvitamin D3 Chemical Structure

CAS No. : 29261-12-9

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1 mg USD 2160 In-stock
Estimated Time of Arrival: December 31
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10 mg USD 9360 In-stock
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Description

25,26-Dihydroxyvitamin D3(25,26-dihydroxycholecalciferol) is a metabolite of vitamin D3 with intestinal calcium transport activity. IC50 value: Target: VD metabolite The biological activity of synthetic 24,25 and 25,26 diOHD3 was studied in vitamin D-deficient rats. The purpose of this study was to investigate the influence of small doses of both metabolites (0.125-0.250 mug) upon intestinal calcium transport and bone calcium mobilization. Both metabolites were able to increase calcium absorption in rats maintained on a calcium-deficient diet, but failed to do it in rats on a normal calcium diet. Bilateral nephrectomy suppressed this effect. The "bone calcium mobilization" of both derivatives was measured in vitamin D and calcium- or phosphorus-deprived rats after one intravenous dose. When serum calcium was initially low, 24,25 and 25,26 diOHD3 increased serum calcium moderately, but the increment was only significant with 24,25 diOHD3.

Molecular Weight

416.64

Formula

C₂₇H₄₄O₃

CAS No.

29261-12-9

SMILES

C[[email protected]@H]([[email protected]]1CC[[email protected]@]2([H])/C(CCC[[email protected]]12C)=C/C=C3C(CC[[email protected]](O)C\3)=C)CCCC(O)(C)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

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Keywords:

25,26-Dihydroxyvitamin D325,26-DihydroxycholecalciferolVD/VDREndogenous MetaboliteVitamin DVitamin D receptorInhibitorinhibitorinhibit

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25,26-Dihydroxyvitamin D3
Cat. No.:
HY-15830
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