Impurity C of Calcitriol
Based on 1 Customer Validation
Impurity C of Calcitriol is the impurity of Calcitriol (HY-10002). Calcitriol is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
For research use only. We do not sell to patients.
- Purity : 99.84%
- CAS No.: 86307-44-0
- Formula: C35H49N3O5
- Molecular Weight:591.78
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
HY-10001
CalcipotriolVitamin D3 Analog -
HY-50919
ParicalcitolVitamin D Receptor Agonist -
HY-32339
MaxacalcitolVDR Agonist -
HY-13292
Impurity B of CalcitriolDiastereomer -
HY-15254
3-O-(2-Aminoethyl)-25-hydroxyvitamin D3Vitamin D3 Derivative -
HY-10001R
Calcipotriol (Standard)Vitamin D3 Analog -
HY-10001A
Calcipotriol monohydrateVitamin D3 Analog -
HY-13294
Impurity C of AlfacalcidolAlfacalcidol Impurity -
HY-15439
(24S)-24,25-Dihydroxyvitamin D3Vitamin D3 Inactive Form -
HY-75958
Vitamin D4VD/VDR Activator -
HY-75041
Calcitriol Impurities AImpurity Of Calcitriol -
HY-15328
25-Hydroxy VD2-d6Deuterated 25-Hydroxy VD2
Biological Activity
Description
Chemical Information
-
CAS No. 86307-44-0
-
Appearance Solid
-
Molecular Weight 591.78
-
Formula C35H49N3O5
-
Color White to off-white
-
SMILES
O[C@@H](C[C@@H]1O)CC([C@@H]2C=C3[C@@](CC[C@]4([H])[C@@H](CCCC(C)(O)C)C)([H])[C@]4(C)CC[C@@]3([H])N(C(N5C6=CC=CC=C6)=O)N2C5=O)=C1C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (84.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (276 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004) [Content Brief]
[2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. [Content Brief]
[3]. Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23. [Content Brief]
[4]. Alkharfy KM, Al-Daghri NM, Yakout SM, Ahmed M. Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6898 mL | 8.4491 mL | 16.8982 mL | 42.2454 mL |
| 5 mM | 0.3380 mL | 1.6898 mL | 3.3796 mL | 8.4491 mL | |
| 10 mM | 0.1690 mL | 0.8449 mL | 1.6898 mL | 4.2245 mL | |
| 15 mM | 0.1127 mL | 0.5633 mL | 1.1265 mL | 2.8164 mL | |
| 20 mM | 0.0845 mL | 0.4225 mL | 0.8449 mL | 2.1123 mL | |
| 25 mM | 0.0676 mL | 0.3380 mL | 0.6759 mL | 1.6898 mL | |
| 30 mM | 0.0563 mL | 0.2816 mL | 0.5633 mL | 1.4082 mL | |
| 40 mM | 0.0422 mL | 0.2112 mL | 0.4225 mL | 1.0561 mL | |
| 50 mM | 0.0338 mL | 0.1690 mL | 0.3380 mL | 0.8449 mL | |
| 60 mM | 0.0282 mL | 0.1408 mL | 0.2816 mL | 0.7041 mL | |
| 80 mM | 0.0211 mL | 0.1056 mL | 0.2112 mL | 0.5281 mL |
Impurity C of Calcitriol Related Classifications
HY-13293 Related Classifications
Powered by Bioz