Oleic acid sodium (Synonyms: Sodium oleate; 9-cis-Octadecenoic acid sodium; 9Z-Octadecenoic acid sodium)

Name: Oleic acid sodium
Brand: MedChemExpress
SKU: HY-N1446B
Rating: 5.0 (64 reviews)

Cat. No.: HY-N1446B Purity: 99.99%: Data Sheet
COA

SDS
Handling Instructions
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Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na⁺/K⁺ ATPase activator.

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CAS No. : 143-19-1

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	해외재고보유	Estimated Time of Arrival: December 31
Solid
100 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	해외재고보유	Estimated Time of Arrival: December 31
100 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

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고객리뷰

Based on 64 publication(s) in Google Scholar

Other Forms of Oleic acid sodium:

64 Publications Citing Use of MCE Oleic acid sodium

Flow Cytometry

Cell Proliferation/Viability Assay

: Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Feb 3:80:103528. [Abstract]; OVCAR8 and A2780 cells were cultured in fatty acid-free media supplemented with 50 μM AA (arachidonic acid), 50 μM OA (oleic acid), 50 μM EPA (eicosapentaenoic acid), 50 μM PA (Palmitic acid), and 50 μM MA (myristic acid) with the treatment of 10 μM niraparib for 72 h, and the cell viability was determined.

: Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Nov 24;11(1):542. [Abstract]; The results showed that after Oleic acid sodium (OA, 200 µM; 24-72 h) treatment, cells with high PPARα expression (sh) exhibited slower proliferation, whereas cells with low PPARα expression (nc) proliferated faster.

: Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]; Oleic acid (50 μM; 1-4 d) significantly promotes viability in CRC cells (HCT116, HT-29, DLD-1).

: Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]; Oleic acid (50 μM) significantly promotes the proliferation of colorectal cancer (CRC) cells (HCT116, HT-29).

: Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Biochim Biophys Acta Mol Basis Dis. 2024 Jun 25:167314. [Abstract]; SVEC4-10 cells were treated with Oleic acid sodium (Oleate, 200 μM) for 24 h. Lipid droplets were detected by BODIPY staining.

: Oleic acid sodium purchased from MedChemExpress. Usage Cited in: J Extracell Vesicles. 2024 Jan;13(1):e12401. [Abstract]; Oleic acid (500-1000 μM; 24 h) significantly inhibits the activity of ARPE-19 cells.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium^[1]. Sodium oleate is a Na⁺/K⁺ ATPase activator^[2].

IC₅₀ & Target

Na⁺/K⁺ ATPase^[2]

In Vitro

Oleic acid is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Oleic acid prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Oleic acid inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

304.44

화학식

C₁₈H₃₃NaO₂

CAS No.

143-19-1

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCC/C=C\CCCCCCCC(O[Na])=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

선적

Room temperature in continental US; may vary elsewhere.

보관

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

용액&용해도

In Vitro:

H₂O : 25 mg/mL (82.12 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2847 mL	16.4236 mL	32.8472 mL
5 mM	0.6569 mL	3.2847 mL	6.5694 mL
10 mM	0.3285 mL	1.6424 mL	3.2847 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 9.09 mg/mL (29.86 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.99%

Select Batch:

Data Sheet (267 KB) SDS (393 KB)

COA (238 KB) HNMR (240 KB) MS (85 KB) GC (280 KB)

Handling Instructions (2659 KB)

References

[1]. Li S, et al. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS One. 2014 May 13;9(5):e97330. [Content Brief]

[2]. Jack-Hays MG, et al. Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta. 1996 Feb 21;1279(1):43-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.2847 mL	16.4236 mL	32.8472 mL	82.1180 mL
	5 mM	0.6569 mL	3.2847 mL	6.5694 mL	16.4236 mL
	10 mM	0.3285 mL	1.6424 mL	3.2847 mL	8.2118 mL
	15 mM	0.2190 mL	1.0949 mL	2.1898 mL	5.4745 mL
	20 mM	0.1642 mL	0.8212 mL	1.6424 mL	4.1059 mL
	25 mM	0.1314 mL	0.6569 mL	1.3139 mL	3.2847 mL
	30 mM	0.1095 mL	0.5475 mL	1.0949 mL	2.7373 mL
	40 mM	0.0821 mL	0.4106 mL	0.8212 mL	2.0529 mL
	50 mM	0.0657 mL	0.3285 mL	0.6569 mL	1.6424 mL
	60 mM	0.0547 mL	0.2737 mL	0.5475 mL	1.3686 mL
	80 mM	0.0411 mL	0.2053 mL	0.4106 mL	1.0265 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Oleic acid sodium Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oleic acid143-19-1Sodium oleate9-cis-Octadecenoic acid9Z-Octadecenoic acidNa+/K+ ATPaseEnvironmental PollutantsApoptosisSodium potassium pumpEnvironmental ContaminantsmonounsaturatedATPaseInhibitorinhibitorinhibit

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Oleic acid sodium (Synonyms: Sodium oleate; 9-cis-Octadecenoic acid sodium; 9Z-Octadecenoic acid sodium)

고객리뷰

Other Forms of Oleic acid sodium:

Oleic acid sodium Related Antibodies

64 Publications Citing Use of MCE Oleic acid sodium

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

고객리뷰

Oleic acid sodium Related Antibodies

몰농도 계산기

농도 희석 계산기

Complete Stock Solution Preparation Table

Oleic acid sodium Related Classifications

Keywords:

최근 본 상품:

고객리뷰

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report