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  3. Oleic acid sodium

オレイン酸ナトリウム  (Synonyms: Sodium oleate; Oleic acid (sodium); 9-cis-Octadecenoic acid (sodium); 9Z-Octadecenoic acid (sodium))

製品番号: HY-N1446B 純度: 99.99%
COA 取扱説明書 Technical Support

Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na+/K+ ATPase activator.

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CAS 番号 : 143-19-1

容量 価格(税別) 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
USD 55 在庫あり
Solution
10 mM * 1 mL in Water USD 55 在庫あり
Solid
100 mg $50 在庫あり
500 mg $60 在庫あり
1 g $66 在庫あり
5 g $78 在庫あり
10 g $85 在庫あり
25 g $95 在庫あり
50 g $105 在庫あり
100 g $116 在庫あり
> 100 g   お問い合わせ  

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カスタマーレビュー

Based on 64 publication(s) in Google Scholar

Other Forms of Oleic acid sodium:

Top Publications Citing Use of Products

顧客検証

Flow Cytometry
Cell Proliferation/Viability Assay

    Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Feb 3:80:103528.  [Abstract]

    OVCAR8 and A2780 cells were cultured in fatty acid-free media supplemented with 50 μM AA (arachidonic acid), 50 μM OA (oleic acid), 50 μM EPA (eicosapentaenoic acid), 50 μM PA (Palmitic acid), and 50 μM MA (myristic acid) with the treatment of 10 μM niraparib for 72 h, and the cell viability was determined.

    Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Nov 24;11(1):542.  [Abstract]

    The results showed that after Oleic acid sodium (OA, 200 µM; 24-72 h) treatment, cells with high PPARα expression (sh) exhibited slower proliferation, whereas cells with low PPARα expression (nc) proliferated faster.

    Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8.  [Abstract]

    Oleic acid (50 μM; 1-4 d) significantly promotes viability in CRC cells (HCT116, HT-29, DLD-1).

    Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8.  [Abstract]

    Oleic acid (50 μM) significantly promotes the proliferation of colorectal cancer (CRC) cells (HCT116, HT-29).

    Oleic acid sodium purchased from MedChemExpress. Usage Cited in: Biochim Biophys Acta Mol Basis Dis. 2024 Jun 25:167314.  [Abstract]

    SVEC4-10 cells were treated with Oleic acid sodium (Oleate, 200 μM) for 24 h. Lipid droplets were detected by BODIPY staining.

    Oleic acid sodium purchased from MedChemExpress. Usage Cited in: J Extracell Vesicles. 2024 Jan;13(1):e12401.  [Abstract]

    Oleic acid (500-1000 μM; 24 h) significantly inhibits the activity of ARPE-19 cells.
    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium[1]. Sodium oleate is a Na+/K+ ATPase activator[2].

    IC50 & Target

    Na+/K+ ATPase[2]

    体外実験

    Oleic acid is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Oleic acid prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Oleic acid inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    分子量

    304.44

    分子式

    C18H33NaO2

    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    CCCCCCCC/C=C\CCCCCCCC(O[Na])=O

    Structure Classification
    Initial Source
    輸送条件

    Room temperature in continental US; may vary elsewhere.

    保管条件

    Store at room temperature, keep dry and cool

    *In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)

    溶剤 & 溶解度
    体外: 

    H2O : 25 mg/mL (82.12 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.2847 mL 16.4236 mL 32.8472 mL
    5 mM 0.6569 mL 3.2847 mL 6.5694 mL
    10 mM 0.3285 mL 1.6424 mL 3.2847 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます:C1V1 = C2V2

    濃度 (開始)

    C1

    ×
    体積 (開始)

    V1

    =
    濃度 (終了)

    C2

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    体積 (終了)

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    体内:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 9.09 mg/mL (29.86 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

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    (per animal)

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    純度とドキュメンテーション

    純度: 99.99%

    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 3.2847 mL 16.4236 mL 32.8472 mL 82.1180 mL
    5 mM 0.6569 mL 3.2847 mL 6.5694 mL 16.4236 mL
    10 mM 0.3285 mL 1.6424 mL 3.2847 mL 8.2118 mL
    15 mM 0.2190 mL 1.0949 mL 2.1898 mL 5.4745 mL
    20 mM 0.1642 mL 0.8212 mL 1.6424 mL 4.1059 mL
    25 mM 0.1314 mL 0.6569 mL 1.3139 mL 3.2847 mL
    30 mM 0.1095 mL 0.5475 mL 1.0949 mL 2.7373 mL
    40 mM 0.0821 mL 0.4106 mL 0.8212 mL 2.0529 mL
    50 mM 0.0657 mL 0.3285 mL 0.6569 mL 1.6424 mL
    60 mM 0.0547 mL 0.2737 mL 0.5475 mL 1.3686 mL
    80 mM 0.0411 mL 0.2053 mL 0.4106 mL 1.0265 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます:C1V1 = C2V2

    濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    製品名:
    Oleic acid sodium
    製品番号:
    HY-N1446B
    数量:
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