2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Sodium Channel Endogenous Metabolite
  4. Z-Gly-Gly-Phe-OH

Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Z-Gly-Gly-Phe-OH

Z-Gly-Gly-Phe-OH 構造式

CAS 番号 : 13171-93-2

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 82 在庫あり
Solution
10 mM * 1 mL in DMSO USD 82 在庫あり
Solid
100 mg $75 在庫あり
250 mg $120 在庫あり
500 mg   お問い合わせ  
1 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Z-Gly-Gly-Phe-OH 関連抗体

Top Publications Citing Use of Products

Sodium Channel アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
Nav1.1 Nav1.2 Nav1.3 Nav1.4 Nav1.5 Nav1.6 Nav1.7 Nav1.8 Nav1.9

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
Human Endogenous Metabolite Microbial Metabolite

  • 生物活性

  • 純度とドキュメンテーション

  • 参考文献

  • カスタマーレビュー

製品説明

Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis[1][2].

体外実験

Z-Gly-Gly-Phe-OH (25 mM; 80 min) reacts with 50 mM H-Leu-NHPh in ethylene glycol-acetate buffer to generate Z-Gly-Gly-Phe-Leu-NHPh in a pepsin-catalyzed peptide bond synthesis experiment[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Z-Gly-Gly-Phe-OH 関連抗体
分子量

413.42

分子式

C21H23N3O6
CAS 番号
Appearance

Solid

Color

White to light yellow

SMILES

O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(OCC2=CC=CC=C2)=O)=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (241.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4188 mL 12.0942 mL 24.1885 mL
5 mM 0.4838 mL 2.4188 mL 4.8377 mL
10 mM 0.2419 mL 1.2094 mL 2.4188 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.46%

COA (246 KB) HNMR (138 KB) RP-HPLC (237 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4188 mL 12.0942 mL 24.1885 mL 60.4712 mL
5 mM 0.4838 mL 2.4188 mL 4.8377 mL 12.0942 mL
10 mM 0.2419 mL 1.2094 mL 2.4188 mL 6.0471 mL
15 mM 0.1613 mL 0.8063 mL 1.6126 mL 4.0314 mL
20 mM 0.1209 mL 0.6047 mL 1.2094 mL 3.0236 mL
25 mM 0.0968 mL 0.4838 mL 0.9675 mL 2.4188 mL
30 mM 0.0806 mL 0.4031 mL 0.8063 mL 2.0157 mL
40 mM 0.0605 mL 0.3024 mL 0.6047 mL 1.5118 mL
50 mM 0.0484 mL 0.2419 mL 0.4838 mL 1.2094 mL
60 mM 0.0403 mL 0.2016 mL 0.4031 mL 1.0079 mL
80 mM 0.0302 mL 0.1512 mL 0.3024 mL 0.7559 mL
100 mM 0.0242 mL 0.1209 mL 0.2419 mL 0.6047 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Z-Gly-Gly-Phe-OH Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Gly-Gly-Phe-OH13171-93-2Sodium ChannelEndogenous MetaboliteNa channelsNa+ channelsactive compoundsynthesisenzymic peptideInhibitorinhibitorinhibit

最近チェックした製品:

オンラインお問い合わせ

Your information is safe with us. * Required Fields.

製品名

  

カスタマ需要量 *

お名前 *

 

タイトル

メールアドレス *

 

電話番号 *

デパートメント

 

組纖名 *

市区町村

都道府県

国或いは地域 *

      

必ず会社名を記載ください。個人への返信は行いません。

備考

バルクお問い合わせ

Inquiry Information

製品名:
Z-Gly-Gly-Phe-OH
製品番号:
HY-W090942
数量:
MCE 日本正規代理店:

カスタマーレビュー

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

製品名

  

Lot #

お名前 *

 

メールアドレス *

電話番号 *

 

部門 *

組纖名 *

 

国或いは地域 *

備考

Request for HNMR Report

We have received your request and will respond to you as soon as possible.