Z-Gly-Pro-Arg-AMC hydrochloride

Cat. No.: HY-P4217 Pureté: 99.15%: Fiche technique
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Instruction de manipulation
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Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity.

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Synthèse de peptides personnalisée

Z-Gly-Pro-Arg-AMC hydrochloride Chemical Structure

CAS No. : 201928-42-9

Size	Stock	Quantité
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtenir un devis
100 mg	Obtenir un devis

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* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE Z-Gly-Pro-Arg-AMC hydrochloride

•Expert Opin Drug Discov. 2025 Jul 2:1-12. [Abstract]

Recommandations en vedette

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Voir tous les produits spécifiques à Isoform Cathepsin:

Voir toutes les isoformes

Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

Activité biologique
Pureté et documentation
Références
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Description

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity^[1]^[2].

Masse moléculaire

656.13

Formule

C₃₁H₃₈ClN₇O₇

CAS No.

201928-42-9

Appearance

Solid

Color

White to off-white

Sequence

Z-Gly-Pro-Arg-AMC

Sequence Shortening

Z-GPR-AMC

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvant et solubilité

In Vitro:

DMSO : 100 mg/mL (152.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5241 mL	7.6204 mL	15.2409 mL
5 mM	0.3048 mL	1.5241 mL	3.0482 mL
10 mM	0.1524 mL	0.7620 mL	1.5241 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Volume _(start)

Concentration _(final)

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Calculation results:

Working solution concentration: mg/mL

Pureté et documentation

Purity: 99.15%

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Fiche technique (273 KB) SDS (393 KB)

COA (250 KB) RP-HPLC (222 KB) MS (210 KB) Elemental Analysis Report (110 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292. [Content Brief]

[2]. Li WA, et al. Detection of femtomole quantities of mature cathepsin K with zymography. Anal Biochem. 2010 Jun 1;401(1):91-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5241 mL	7.6204 mL	15.2409 mL	38.1022 mL
	5 mM	0.3048 mL	1.5241 mL	3.0482 mL	7.6204 mL
	10 mM	0.1524 mL	0.7620 mL	1.5241 mL	3.8102 mL
	15 mM	0.1016 mL	0.5080 mL	1.0161 mL	2.5401 mL
	20 mM	0.0762 mL	0.3810 mL	0.7620 mL	1.9051 mL
	25 mM	0.0610 mL	0.3048 mL	0.6096 mL	1.5241 mL
	30 mM	0.0508 mL	0.2540 mL	0.5080 mL	1.2701 mL
	40 mM	0.0381 mL	0.1905 mL	0.3810 mL	0.9526 mL
	50 mM	0.0305 mL	0.1524 mL	0.3048 mL	0.7620 mL
	60 mM	0.0254 mL	0.1270 mL	0.2540 mL	0.6350 mL
	80 mM	0.0191 mL	0.0953 mL	0.1905 mL	0.4763 mL
	100 mM	0.0152 mL	0.0762 mL	0.1524 mL	0.3810 mL