9,10-Dihydroxystearic acid

Name: 9,10-Dihydroxystearic acid
Brand: MedChemExpress
SKU: HY-N8522
Rating: 4.5 (0 reviews)

Art. -Nr.: HY-N8522 Reinheit: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice.

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9,10-Dihydroxystearic acid Chemische Struktur

CAS. Nr. : 120-87-6

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
1 mg	Auf Lager	Estimated Time of Arrival: December 31
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Angebot einholen
50 mg	Angebot einholen

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Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität
Reinheit & Dokumentation
Verweise
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Beschreibung

9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice^[1].

In Vitro

5-20 μmol/L 9,10-Dihydroxystearic acid (DHSA) does not activate PPAR-γ in CV-1 cells but 50-100 μmol/L DHSA activates PPAR-γ in a dose-dependent way. 9,10-Dihydroxystearic acid does not activate PPAR-α in CV-1 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

9,10-Dihydroxystearic acid (DHSA; fed with high fat diet containing 4% DHSA; for 5-6 weeks) treatment improves glucose tolerance and insulin sensitivity in KKAy mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

316.48

Formel

C₁₈H₃₆O₄

CAS. Nr.

120-87-6

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCC(O)C(O)CCCCCCCC(O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 125 mg/mL (394.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1598 mL	15.7988 mL	31.5976 mL
5 mM	0.6320 mL	3.1598 mL	6.3195 mL
10 mM	0.3160 mL	1.5799 mL	3.1598 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 98.0%

Select Batch:

Data Sheet (266 KB) SDS (393 KB)

COA (239 KB) HNMR (259 KB) MS (70 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Xiaoming Yu, et al. Effects of 9,10-dihydroxysteatic acid on glucose metabolism in KKAy mice. Wei Sheng Yan Jiu. 2010 Jul;39(4):423-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1598 mL	15.7988 mL	31.5976 mL	78.9939 mL
	5 mM	0.6320 mL	3.1598 mL	6.3195 mL	15.7988 mL
	10 mM	0.3160 mL	1.5799 mL	3.1598 mL	7.8994 mL
	15 mM	0.2107 mL	1.0533 mL	2.1065 mL	5.2663 mL
	20 mM	0.1580 mL	0.7899 mL	1.5799 mL	3.9497 mL
	25 mM	0.1264 mL	0.6320 mL	1.2639 mL	3.1598 mL
	30 mM	0.1053 mL	0.5266 mL	1.0533 mL	2.6331 mL
	40 mM	0.0790 mL	0.3950 mL	0.7899 mL	1.9748 mL
	50 mM	0.0632 mL	0.3160 mL	0.6320 mL	1.5799 mL
	60 mM	0.0527 mL	0.2633 mL	0.5266 mL	1.3166 mL
	80 mM	0.0395 mL	0.1975 mL	0.3950 mL	0.9874 mL
	100 mM	0.0316 mL	0.1580 mL	0.3160 mL	0.7899 mL