2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Flavin adenine dinucleotide disodium salt

Flavin adenine dinucleotide disodium salt  (Synonyms: FAD disodium salt; FAD-Na2)

Cat. No.: HY-B1654A Pureza: 99.72%
COA
SDS
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Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

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No. CAS : 84366-81-4

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Revisión del cliente

Based on 8 publication(s) in Google Scholar

Other Forms of Flavin adenine dinucleotide disodium salt:

Flavin adenine dinucleotide disodium salt Related Antibodies

Top Publications Citing Use of Products

    Flavin adenine dinucleotide disodium salt purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Hep3B and HCCLM3 cells treated with Riboflavin (VB2; 10 µM), Riboflavin phosphate sodium (FMN; 10 µM), Flavin adenine dinucleotide (FAD; 10 µM), or PBS (Ctrl) for 48 h, followed by CCK-8 assay.

    Flavin adenine dinucleotide disodium salt purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Relative mRNA levels of interferon-stimulated genes (ISG15, IFIT1, IFNB1) and chemokines (CCL5, CXCL9, CXCL10) in Hep3B cells (n = 3 biological replicates). Flavin adenine dinucleotide (FAD), 20 µM for 48 h; H-151 (STING inhibitor), 1 μM for 12 h.

    Flavin adenine dinucleotide disodium salt purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Levels of ROS and lipid peroxidation in Hep3B cells (n = 3 biological replicates). Flavin adenine dinucleotide (FAD), 20 µM for 48 h.

    Flavin adenine dinucleotide disodium salt purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    GR activity, GSH levels, and GSH/GSSG ratio in Hep3B cells (n = 4 biological replicates). Flavin adenine dinucleotide (FAD), 20 µM for 48 h.

    Flavin adenine dinucleotide disodium salt purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Oct 29;16(1):9547.  [Abstract]

    Hep3B cells with FADS-knockdown treated with VB2 (10 µM), FMN (10 µM), Flavin adenine dinucleotide (FAD;10 µM), or PBS (Ctrl) for 48 h, followed by CCK-8 assay.

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    • Actividad biológica

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    • Revisión del cliente

    Descripciòn

    Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    In Vitro

    Poly(Flavin adenine dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Flavin adenine dinucleotide disodium salt Related Antibodies
    In Vivo

    With Flavin adenine dinucleotide (2 mg/kg), the chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT) is significantly cancelled. Flavin adenine dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin adenine dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin adenine dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Peso molecular

    829.51

    Fòrmula

    C27H31N9Na2O15P2
    No. CAS
    Appearance

    Solid

    Color

    Yellow to orange

    SMILES

    NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@@H](O)[C@@H](O)[C@@H](O)CN4C(C(C(N5)=O)=NC6=C4C=C(C)C(C)=C6)=NC5=O)(O[Na])=O)(O[Na])=O)O3
    Structure Classification
    Initial Source
    Envío

    Room temperature in continental US; may vary elsewhere.
    Almacenamiento

    4°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    Solvente y solubilidad
    In Vitro: 

    H2O : 33.33 mg/mL (40.18 mM; Need ultrasonic)

    DMSO : 5 mg/mL (6.03 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.2055 mL 6.0277 mL 12.0553 mL
    5 mM 0.2411 mL 1.2055 mL 2.4111 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Calculadora de molaridad

    • Calculadora de dilución

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Pureza y Documentación

    Purity: 99.72%

    SDS (393 KB)

    COA (252 KB) HNMR (328 KB) RP-HPLC (276 KB) MS (68 KB)

    Instrucciones de manejo (2659 KB)
    Referencias

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO / H2O 1 mM 1.2055 mL 6.0277 mL 12.0553 mL 30.1383 mL
    5 mM 0.2411 mL 1.2055 mL 2.4111 mL 6.0277 mL
    H2O 10 mM 0.1206 mL 0.6028 mL 1.2055 mL 3.0138 mL
    15 mM 0.0804 mL 0.4018 mL 0.8037 mL 2.0092 mL
    20 mM 0.0603 mL 0.3014 mL 0.6028 mL 1.5069 mL
    25 mM 0.0482 mL 0.2411 mL 0.4822 mL 1.2055 mL
    30 mM 0.0402 mL 0.2009 mL 0.4018 mL 1.0046 mL
    40 mM 0.0301 mL 0.1507 mL 0.3014 mL 0.7535 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Flavin adenine dinucleotide disodium salt Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Flavin adenine dinucleotide disodium84366-81-4FAD disodium FAD-Na2Endogenous MetaboliteInhibitorinhibitorinhibit

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    Nombre del producto:
    Flavin adenine dinucleotide disodium salt
    Cat. No.:
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