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Hesperidin (Synonyms: Hesperetin 7-rutinoside)

Cat. No.: HY-15337 Purity: 97.47%
Handling Instructions

Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange.

For research use only. We do not sell to patients.
Hesperidin Chemical Structure

Hesperidin Chemical Structure

CAS No. : 520-26-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
10 mg USD 60 In-stock
50 mg USD 108 In-stock
100 mg USD 144 In-stock
200 mg USD 192 In-stock
500 mg USD 228 In-stock
1 g USD 348 In-stock
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Customer Review

    Hesperidin purchased from MCE. Usage Cited in: Cell Rep. 2017 Nov 21;21(8):2147-2159.

    U2OS cells expressing Myc-tagged PLK1 WT, K492R, or SUMO-1-K492R are treated with Taxol for 16 hr. Half of the cells are then released in the presence of Hesperidin for 45 min to enrich cells at the later stage of M phase. Cell lysates are subject to IP, followed by western blot.
    • Biological Activity

    • Protocol

    • Technical Information

    • Purity & Documentation

    • References


    Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange. Hesperidin is used effectively as a supplemental agent in complementary therapy protocols, since it possesses biological and pharmacological properties as an effective antioxidant, anti-inflammatory, anti-carcinogenic, and anti-hypertensive agent with lipid-lowering activity[1] IC50: hesperidin (IC50=116.68μmo/L))[4] in vitro: hesperidin and linarin are two of the main constituent of Valeriana's extract exhibiting a high affinity to KATP channel, which are related to the control of Ca++ concentration and release of GABA in synaptic nerve terminal, mainly on cells of SN[2] in vivo: Hesperidin was dissolved in 1% carboxymethyl cellulose (CMC) and administered orally at a dose of 50 mg/kg for 10 consecutive days. In the control group, rats were treated with the corn oil and 1% CMC vehicle.[1]

    Clinical Trial
    Molecular Weight




    CAS No.



    OC1=C(OC)C=CC([[email protected]@H]2CC(C3=C(C=C(O[[email protected]@H]4O[[email protected]](CO[[email protected]@H]5O[[email protected]@H](C)[[email protected]](O)[[email protected]@H](O)[[email protected]]5O)[[email protected]@H](O)[[email protected]](O)[[email protected]]4O)C=C3O)O2)=O)=C1

    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month

    Room temperature in continental US; may vary elsewhere

    Solvent & Solubility

    10 mM in DMSO

    * "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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