2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N10631
    Paucimannose 70858-45-6
    Paucimannose is a mannosidic N-glycan epitope. It acts as a carcinoembryonic antigen, and a marker for cancer, stem cell properties and inflammation. Paucimannose mainly exists in plants and invertebrates. It consists of oligomannose-type N-glycans that preferentially bind to mannose-binding lectin. Paucimannose localizes on the surface of resting cells and translocates upon cell activation. It can be used in studies related to Pseudomonas aeruginosa infection, cancer and pancreatitis.
    Paucimannose
  • HY-N1067R
    Xanthohumol (Standard) 6754-58-1 99.30%
    Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol (Standard)
  • HY-N10895
    12-Hydroxyisobakuchiol 178765-55-4 98.74%
    12-Hydroxyisobakuchiol is a hemiterpenoid compound that can be isolated from the leaves of Psoralea glandulosa. 12-Hydroxyisobakuchiol inhibits mycelial growth of Botrytis cinerea in vitro. 12-Hydroxyisobakuchiol is applicable to research related to phytopathogenic fungal infections.
    12-Hydroxyisobakuchiol
  • HY-N11546
    Sapindoside B 30994-75-3
    Sapindoside B is a substance with hepatoprotective activity, and also acts as a cytochrome P-450 (cytochrome P-450) inhibitor, antibacterial agent and membrane-disrupting agent. Sapindoside B reversibly inhibits the content of cytochrome P-450 in liver microsomes, suppresses the phenobarbital-induced increase in enzyme content, reduces the production of active metabolites mediated by cytochrome P-450, and alleviates hepatotoxic injury. Sapindoside B binds to Cutibacterium acnes lipase, reduces lipase activity, inhibits biofilm formation, and decreases bacterial adhesion. Sapindoside B exhibits cytotoxicity against human cancer, liver cancer, leukemia and glioblastoma cells. Sapindoside B inhibits mycelial growth of phytopathogenic fungal strains, possesses antibacterial activity against dermatophytes, and also has hemolytic/membrane-lytic activity. Sapindoside B can be used in research related to liver injury, Cutibacterium acnes biofilm-associated infections, gastric cancer, carcinoma, promyelocytic leukemia, glioblastoma, apple scab and grape gray mold.
    Sapindoside B
  • HY-N12077
    Eurycomanol 2-O-β-D-glucopyranoside 126260-97-7 99.79%
    Eurycomanol 2-O-β-D-glucopyranoside (compound 4) is a natural product that can be obtained from Eurycoma longifolia. Eurycomanol 2-O-β-D-glucopyranoside has the potential for anti-malarial research.
    Eurycomanol 2-O-β-D-glucopyranoside
  • HY-N12343
    Tetrahydrorhombifoline 3382-84-1
    Tetrahydrorhombifoline is one of quinolizidine alkaloids in the aerial parts of Genista vuralii A. Duran & H. Dural (Fabaceae). The alkaloid extract of G. vuralii has antibacterial and antifungal activities.
    Tetrahydrorhombifoline
  • HY-N12352
    Eschweilenol C 211371-02-7 98%
    Eschweilenol C is a selective Plasmodium falciparum growth inhibitor. Eschweilenol C disrupts haemoglobin metabolism, reduces haemozoin production, kills Plasmodium falciparum ring and trophozoite stages. Eschweilenol C can be used for the research of inflammatory disorders and malaria.
    Eschweilenol C
  • HY-N12677
    Isocannflavin B 199167-23-2 99.9%
    Isocannflavin B (Caflanone) is a flavonoid compound. Isocannflavin B exhibits anti-tumor and anti-viral activities. Isocannflavin B induces apoptosis, autophagy and cell cycle arrest in tumor cells, and inhibits cell proliferation. Isocannflavin B inhibits HCoV-OC43. Isocannflavin B can be used in research related to cancer and COVID-19.
    Isocannflavin B
  • HY-N12908
    Roridin H 29953-50-2 98%
    Roridin H (Verrucarin H) is an antibiotic and can be isolated from Myrothecium verrucaria.
    Roridin H
  • HY-N13286
    Glycozolidal 51971-09-6 99.92%
    Glycozolidal (compound 12) is a carbazole alkaloid with antibacterial activity against P. gingivalis. Glycozolidal is cytotoxic against human gingival fibroblasts (HGFs) and monocytes (U937) in vitro with IC50 values ​​of 120.86 µg/mL and 97.74 µg/mL, respectively.
    Glycozolidal
  • HY-N13363
    2-Keto-3-deoxy-6-phosphogluconate 27244-54-8 98%
    2-keto-3-deoxy-6-phosphogluconate is an endogenous metabolite found in Escherichia coli, and a key intermediate in the Entner-Doudoroff (ED) pathway, as well as in the degradation pathways of sugar acids and sugar polymers in human and plant pathogens. It is produced by the catalytic action of KDPG aldolase.
    2-Keto-3-deoxy-6-phosphogluconate
  • HY-N13871
    Anguibactin 104245-09-2 98%
    Anguibactin is an antibiotic that acts as a siderophore. Anguibactin has a strong affinity with Fe3+.
    Anguibactin
  • HY-N13920
    Avilamycin C 69787-80-0 98%
    Avilamycin C is an avilamycin-type antibiotic. Avilamycin C has antibacterial activity and can inhibit Gram-positive bacteria.
    Avilamycin C
  • HY-N1480R
    (-)-Fucose (Standard) 2438-80-4 99.88%
    (-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth.
    (-)-Fucose (Standard)
  • HY-N15117
    Polymyxin P1 37331-24-1 98%
    Polymyxin P1 is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 can be used for the research of fire blight and soft rot.
    Polymyxin P1
  • HY-N15435
    Conimine 468-41-7 98%
    Conimine is a steroidal alkaloid, antibacterial agent and potentiator. Conimine is isolated from the seeds of Holarrhena antidysenteriaca Wall.ex A.DC. Conimine exhibits intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. When combined with Penicillin, Conimine shows synergistic antibacterial effects against methicillin-resistant Staphylococcus aureus; when combined with Vancomycin (HY-B0671), it exerts synergistic antibacterial effects against both methicillin-sensitive and methicillin-resistant Staphylococcus aureus.
    Conimine
  • HY-N1584R
    Halofuginone (Standard) 55837-20-2 99.73%
    Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical applications. Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
    Halofuginone (Standard)
  • HY-N16395
    Jensenone 96573-43-2
    Jensenone is an acylphloroglucinol derivative. Jensenone binds to COVID-19 proteinase in molecular docking studies. Jensenone can be used as a COVID-19 Mpro inhibitor.
    Jensenone
  • HY-N18050
    Petrobactin 545434-89-7 98%
    Petrobactin is a photoreactive siderophore. Petrobactin can be produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. Petrobactin can be synthesized by Bacillus anthracis str. Sterne under conditions of iron starvation. Petrobactin readily undergoes a light-mediated decarboxylation reaction when bound to Fe(III).
    Petrobactin
  • HY-N1952S
    Isoeugenol-d3 98%
    Isoeugenol-d3 is deuterated labeled Isoeugenol (HY-N1952). Isoeugenol is an essential oil constituent of nutmeg, clove, and cinnamon. Isoeugenol inhibits growth of Escherichia coli and Listeria innocua with MICs of 0.6 mg/mL and 1 mg/mL, respectively.
    Isoeugenol-d3
Cat. No. Product Name / Synonyms Application Reactivity