Infection

Related Products

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Infection Related Products (17859)
Antibodies (22)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-123652

Etofamide	25287-60-9	98%
Etofamide is an antimicrobial agent with IC₅₀ value of 5.96 mg/L against amoeba.

HY-123686

Ivermectin B1a monosaccharide	71837-27-9	98%
Ivermectin B1a monosaccharide is a modified Ivermectin B1a (HY-126937). Ivermectin B1a monosaccharide is an antiparasite agent with a minimum concentration for full activity in Haemonchus contortus larval development of 0.001 μg/mL.

HY-123711

PC170942	867207-49-6	98%
PC170942, a PC58538 analogue, is a potent FtsZ protein inhibitor. PC170942 is a cell division inhibitor, and shows antibacterial activities.

HY-123767

HEC72702	1793063-59-8	98%
HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC₅₀ values of 0.039 µM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers.

HY-123808

MK-8325	1334312-52-5	98%
MK-8325 (Compound 1) is an orally active HCV NS5A inhibitor. MK-8325 exhibits minimal inhibitory activity against hERG at a concentration of 30 mM. MK-8325 may be used in hepatitis C research.

HY-123887

Manumycin B	139023-58-8	98%
Manumycin B is an antibiobic, and exhibits antitumor activity. Manumycin B is an inhibitor for acetylcholinesterase (AChE) with an IC₅₀ of 15 mM.

HY-123897

Chamaejasmenin C	89595-70-0	98%
Chamaejasmenin C, a biflavanone, shows nematicidal activity against second-stage juveniles (J2s) of B. xylophilus and B. mucronatus.

HY-123902

Ophiobolin C	19022-51-6	98%
Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells. Ophiobolin C is also cytotoxic to chronic lymphocytic leukemia cells.

HY-123915

Antimalarial agent 20	1422207-75-7	98%
Antimalarial agent 20 (Compound 49c) is an antimalarial agent with an IC₅₀ of 0.6 nM against P. falciparum NF54 parasite strain in the NF54 albumax assay.

HY-123996

3-Ethoxy-5,6-dibromosalicylaldehyde	20041-64-9	98%
3-ethoxy-5,6-dibromosalicylaldehyde is a potent, non-competitive, selective IRE1 (including IRE1α) inhibitor (IC₅₀s: ∼0.12 μM for hIRE1α-cyto; 6 μM for yeast Ire1). 3-ethoxy-5,6-dibromosalicylaldehyde inhibits XBP-1 splicing. 3-ethoxy-5,6-dibromosalicylaldehyde induces Apoptosis. 3-ethoxy-5,6-dibromosalicylaldehyde upregulates the mRNA expression level of TXNIP, while downregulating the expression level of TXN. 3-ethoxy-5,6-dibromosalicylaldehyde exhibits anticancer activity against pancreatic cancer. 3-ethoxy-5,6-dibromosalicylaldehyde significantly inhibits chikungunya virus replication.

HY-124035

Streptochlorin	120191-51-7	98%
Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC₅₀ value of 230 ng/ml for GUTat 3.1.

HY-124112

PAM 1392	13794-65-5	98%
PAM 1392 is active orally against *Plasmodium berghei* in mice, *P. cynofologi* and *P. knowlesi* in monkeys and *Trypanosoma cruzi* in tissue cultures of mice, and *hemolytic streptococci* in vitro. PAM 1392 has antimalarial and antitrypanosomal activities, which is proming for rasearch of drug-resistant malaria.

HY-124138

Pikromycin	19721-56-3	98%
Pikromycin is a macrolide antibiotic that has been found in S. venezuelae and active against E. coli, S. aureus and B. subtilis.

HY-124162

Diepoxin σ	152697-41-1	98%
Diepoxin σ (Sch-49209) is a highly oxygenated antifungal and anticancer natural product. Diepoxin σ can be isolated from the fermentation of N. mangiferae.

HY-124182

Odalasvir	1415119-52-6	98%
Odalasvir (ACH-3102) is a potent and selective inhibitor of HCV NS5A, and can be used in research on hepatitis C virus infection.

HY-124199

Cephalochromin	25908-26-3	98%
Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI). Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC₅₀ of 1.9 and 1.8 μM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 µg/mL.

HY-124205

Pepticinnamin E	147317-36-0	98%
Pepticinnamin E is a Farnesyltransferase (FTase) inhibitor (IC₅₀=42 µM). Pepticinnamin E can be used in cancer and malaria research.

HY-124210

Formycin B	13877-76-4	98%
Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia.

HY-124250

9-OxoOTrE	125559-74-2	98%
9-OxoOTrE (9-KOTrE) is an antifungal agent against B. cinerea, C. herbarum, P. infestans, and P. parasitica, through a mechanism based on their electrophilic nature.

HY-12429A

Beclabuvir hydrochloride	958002-36-3	98%
Beclabuvir (BMS-791325) hydrochloride is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC₅₀ of < 28 nM.

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Infection

Infection

Infection Related Products (17859)

Antibodies (22)

Infection Related Products (17859):