PAM 1392
PAM 1392 is active orally against Plasmodium berghei in mice, P. cynofologi and P. knowlesi in monkeys and Trypanosoma cruzi in tissue cultures of mice, and hemolytic streptococci in vitro. PAM 1392 has antimalarial and antitrypanosomal activities, which is proming for rasearch of drug-resistant malaria.
For research use only. We do not sell to patients.
- CAS No.: 13794-65-5
- Formula: C15H13Cl2N5
- Molecular Weight:334.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 13794-65-5
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Molecular Weight 334.20
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Formula C15H13Cl2N5
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SMILES
NC1=NC(N)=C2C=C(NCC3=CC=C(Cl)C(Cl)=C3)C=CC2=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Shepard CC. Further experience with the kinetic method for the study of drugs against Mycobacterium leprae in mice. Activities of DDS, DFD, ethionamide, capreomycin and PAM 1392. Int J Lepr Other Mycobact Dis. 1969 Oct-Dec;37(4):389-97. [Content Brief]
[2]. Thompson PE, et al. PAM 1392 (2,4-diamino-6-(3,4-dichlorobenzylamino) quinazoline) as a chemotherapeutic agent: Plasmodium berghei, P. cynomolgi, P. Exp Parasitol. 1969 Aug;25(1):32-49. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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