2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7266
    Obtusifoliol 16910-32-0 99.86%
    Obtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with Kd values of 1.2 μM and 1.4 μM for Trypanosoma brucei (TB) and human CYP51, respectively.
    Obtusifoliol
  • HY-N7677
    Isookanin 1036-49-3 99.76%
    Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity.
    Isookanin
  • HY-N7814
    2-Hydroxypalmitic acid 764-67-0
    2-Hydroxypalmitic acid is an intermediate in the phytosphingosine metabolic pathway. 2-Hydroxypalmitic acid is exclusively incorporated into sphingolipids and not used for other lipids. 2-Hydroxypalmitic acid promotes the production of odd-carbon phosphatidylcholine species. 2-Hydroxypalmitic acid is applicable to studies of Saccharomyces cerevisiae infection.
    2-Hydroxypalmitic acid
  • HY-P1958
    Histone H4 (2-21) 667899-73-2 98.71%
    Histone H4 (2-21) is the core histones associated with chromatinization of herpes simplex virus 1 (HSV-1) genomes.
    Histone H4 (2-21)
  • HY-P2324
    Gramicidin A 11029-61-1 ≥98.0%
    Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
    Gramicidin A
  • HY-Y0258
    Benzocaine 94-09-7 99.98%
    Benzocaine is an orally active local anesthetic. Benzocaine non-competitively inhibits the binding of Ca-ATPase to Ca2+, with an IC50 of 47.1 mM. Benzocaine exerts anesthetic effects by blocking voltage-gated sodium channels. Benzocaine induces methemoglobinemia in various experimental animals.
    Benzocaine
  • HY-Y1162
    1-Methylindole 603-76-9 ≥98.0%
    1-Methylindole is an intermediate. 1-Methylindole can be used in the synthesis of 1-Methyl-indole-3-carboxaldehyde. 1-Methyl-indole-3-carboxaldehyde has anti-Toxoplasma activity.
    1-Methylindole
  • HY-105231
    Bryostatin 1 83314-01-6 ≥99.0%
    Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties.
    Bryostatin 1
  • HY-107373
    β-Chloro-L-alanine 2731-73-9
    β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.
    β-Chloro-L-alanine
  • HY-111529
    Tafenoquine 106635-80-7 99.77%
    Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent.
    Tafenoquine
  • HY-112589
    BRITE-338733 503105-88-2 98.93%
    BRITE-338733 is an inhibitor of E. coli RecA ATPase activity (IC50: 4.7 μM). BRITE-338733 also inhibits the ATP hydrolysis activity of RSC chromatin remodeling enzyme by binding to its ATP-binding pocket and DNA (IC50: 0.316 μM). BRITE-338733 exhibits cytotoxicity against MCF-7 and MDA-MB-231 breast cancer cells. BRITE-338733 can be used in studies on antibacterial adjuvants and anticancer research.
    BRITE-338733
  • HY-113041
    Prostaglandin A2 13345-50-1 ≥98.0%
    Prostaglandin A2 (PGA2) is a Cyclopentenone prostaglandin. Prostaglandin A2 induces Caspase-dependent Apoptosis, activates p53. Prostaglandin A2 activates ERK2 and JNK1/SAPK. Prostaglandin A2 shows antiviral activity against HSV-1. Prostaglandin A2 has anti-tumor effects. Prostaglandin A2 can be used for the research of colorectal cancer, colorectal carcinoma, breast carcinoma, and herpetic keratitis.
    Prostaglandin A2
  • HY-116872
    MAC13772 4871-40-3 99.33%
    MAC13772 is a BioA inhibitor with an IC50 of 0.28 μM against E. coli and an IC50 of 0.269 μM against A. baumannii. MAC13772 inhibits bacterial growth by targeting the biotin biosynthesis pathway. MAC13772 can be used in studies related to bacterial infections.
    MAC13772
  • HY-121310
    Phthalocyanine 574-93-6
    Phthalocyanine is a type of pigment and Photosensitizer. Upon irradiation, Phthalocyanine generates ROS or converts light energy into heat, inducing oxidative damage, cytotoxicity, and photodynamic killing of bacterial biofilms. Phthalocyanine produces chemiluminescence when oxidized. It can be used in studies related to cancer, bacterial infections, and photodynamic approaches.
    Phthalocyanine
  • HY-121618
    α-Thujone 546-80-5 98.07%
    α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and can cross the blood-brain barrier.
    α-Thujone
  • HY-121969
    DDX3-IN-2 1919828-81-1 99.54%
    DDX3-IN-2 is an active DEADbox polypeptide 3 (DDX3) inhibitor with an IC50 value of 0.3 μM. DDX3-IN-2 shows a broad spectrum of antiviral activity. DDX3-IN-2 has the potential to overcome HIV resistance.
    DDX3-IN-2
  • HY-123037
    Triadimefon 43121-43-3 98.12%
    Triadimefon is an orally active fungicide. Triadimefon significantly reduces the phosphorylation of AKT1 and ERK1/2. Triadimefon significantly increases pAMPK levels, but does not affect total AMPK levels. Triadimefon inhibits the growth of Saccharomyces cerevisiae, disrupts hormone homeostasis (affecting the synthesis of testosterone, etc.), inhibits fetal adrenal development in rats, induces metabolic shifts in hepatocytes, and impairs spatial learning and memory.
    Triadimefon
  • HY-123295
    HDAC3-IN-T247 1451042-18-4 98.91%
    HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells.
    HDAC3-IN-T247
  • HY-125168
    EGA 415687-81-9 ≥99.0%
    EGA is an inhibitor that selectively targets the endosomal trafficking pathways. EGA targets the proteins involved in the endosomal trafficking pathways through which multiple toxins and viruses enter cells. EGA exerts its activity by inhibiting the trafficking from early endosomes to late endosomes, blocking the entry of multiple acid-dependent bacterial toxins and viruses into mammalian cells and delaying the lysosomal targeting and degradation of EGFR.
    EGA
  • HY-126085
    (±)-Alliin 17795-26-5 ≥98.0%
    (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro).
    (±)-Alliin
Cat. No. Product Name / Synonyms Application Reactivity