β-Chloro-L-alanine (Synonyms: L-β-Chloroalanine)

Name: β-Chloro-L-alanine
Brand: MedChemExpress
SKU: HY-107373
Rating: 4.5 (1 reviews)

Cat. No.: HY-107373 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.

For research use only. We do not sell to patients.

β-Chloro-L-alanine Chemical Structure

CAS No. : 2731-73-9

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in Water ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of β-Chloro-L-alanine:

3-Chloro-L-alanine Hydrochloride Get quote

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Description

β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.

IC₅₀ & Target

Bacterial^[1]

In Vitro

β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

123.54

Formula

C₃H₆ClNO₂

CAS No.

2731-73-9

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCl)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : ≥ 30 mg/mL (242.84 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.0945 mL	40.4727 mL	80.9454 mL
5 mM	1.6189 mL	8.0945 mL	16.1891 mL
10 mM	0.8095 mL	4.0473 mL	8.0945 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 50 mg/mL (404.73 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (282 KB) SDS (0 KB)

COA (247 KB) HNMR (104 KB)

Handling Instructions (2659 KB)

References

[1]. β-Chloro-L-alanine can inhibits threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escheri [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg

H₂O 1 mM 8.0945 mL 40.4727 mL 80.9454 mL 202.3636 mL

5 mM 1.6189 mL 8.0945 mL 16.1891 mL 40.4727 mL

10 mM 0.8095 mL 4.0473 mL 8.0945 mL 20.2364 mL

15 mM 0.5396 mL 2.6982 mL 5.3964 mL 13.4909 mL

20 mM 0.4047 mL 2.0236 mL 4.0473 mL 10.1182 mL

25 mM 0.3238 mL 1.6189 mL 3.2378 mL 8.0945 mL

30 mM 0.2698 mL 1.3491 mL 2.6982 mL 6.7455 mL

40 mM 0.2024 mL 1.0118 mL 2.0236 mL 5.0591 mL

50 mM 0.1619 mL 0.8095 mL 1.6189 mL 4.0473 mL

60 mM 0.1349 mL 0.6745 mL 1.3491 mL 3.3727 mL

80 mM 0.1012 mL 0.5059 mL 1.0118 mL 2.5295 mL

100 mM 0.0809 mL 0.4047 mL 0.8095 mL 2.0236 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Remarks

β-Chloro-L-alanine Related Classifications

Anti-infection

Bacterial

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Chloro-L-alanine2731-73-9L-β-ChloroalanineBacterialInhibitorinhibitorinhibit

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H₂O	1 mM	8.0945 mL	40.4727 mL	80.9454 mL	202.3636 mL
	5 mM	1.6189 mL	8.0945 mL	16.1891 mL	40.4727 mL
	10 mM	0.8095 mL	4.0473 mL	8.0945 mL	20.2364 mL
	15 mM	0.5396 mL	2.6982 mL	5.3964 mL	13.4909 mL
	20 mM	0.4047 mL	2.0236 mL	4.0473 mL	10.1182 mL
	25 mM	0.3238 mL	1.6189 mL	3.2378 mL	8.0945 mL
	30 mM	0.2698 mL	1.3491 mL	2.6982 mL	6.7455 mL
	40 mM	0.2024 mL	1.0118 mL	2.0236 mL	5.0591 mL
	50 mM	0.1619 mL	0.8095 mL	1.6189 mL	4.0473 mL
	60 mM	0.1349 mL	0.6745 mL	1.3491 mL	3.3727 mL
	80 mM	0.1012 mL	0.5059 mL	1.0118 mL	2.5295 mL
	100 mM	0.0809 mL	0.4047 mL	0.8095 mL	2.0236 mL

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β-Chloro-L-alanine (Synonyms: L-β-Chloroalanine)

Customer Review

Other Forms of β-Chloro-L-alanine:

β-Chloro-L-alanine Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

β-Chloro-L-alanine Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

β-Chloro-L-alanine Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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