β-Chloro-L-alanine
Based on 1 publication(s) in Google Scholar
β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2731-73-9
- Formula: C3H6ClNO2
- Molecular Weight:123.54
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Anti-Infection Compound Library
HY-L002
-
Antibacterial Compound Library
HY-L049
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
Amino Acid Metabolism Compound Library
HY-L189
-
Protein Kinase Compound Library
HY-L196
-
Non-natural Amino Acid Compound Library
HY-L198
-
High-Throughput Bioactive Compound Library
HY-L205
-
3D Diverse Fragment Library
HY-L903
Publications Citing Use of MedChemExpress (MCE) β-Chloro-L-alanine
More
Biological Activity
Bacterial[1]
β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2731-73-9
-
Appearance Solid
-
Molecular Weight 123.54
-
Formula C3H6ClNO2
-
Color White to off-white
-
SMILES
OC([C@@H](N)CCl)=O
-
Synonyms
L-β-Chloroalanine
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
bioRxiv
TGF-β Coordinates Alanine Synthesis and Import for Myofibroblast Differentiation in Pulmonary Fibrosis. [Abstract]2025 Jul 24:2025.07.23.666333. PMID: 40777505
Solvent & Solubility
H2O : ≥ 30 mg/mL (242.84 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (404.73 mM); Clear solution; Need ultrasonic
Purity & Documentation
-
Data Sheet (283 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.0945 mL | 40.4727 mL | 80.9454 mL | 202.3636 mL |
| 5 mM | 1.6189 mL | 8.0945 mL | 16.1891 mL | 40.4727 mL | |
| 10 mM | 0.8095 mL | 4.0473 mL | 8.0945 mL | 20.2364 mL | |
| 15 mM | 0.5396 mL | 2.6982 mL | 5.3964 mL | 13.4909 mL | |
| 20 mM | 0.4047 mL | 2.0236 mL | 4.0473 mL | 10.1182 mL | |
| 25 mM | 0.3238 mL | 1.6189 mL | 3.2378 mL | 8.0945 mL | |
| 30 mM | 0.2698 mL | 1.3491 mL | 2.6982 mL | 6.7455 mL | |
| 40 mM | 0.2024 mL | 1.0118 mL | 2.0236 mL | 5.0591 mL | |
| 50 mM | 0.1619 mL | 0.8095 mL | 1.6189 mL | 4.0473 mL | |
| 60 mM | 0.1349 mL | 0.6745 mL | 1.3491 mL | 3.3727 mL | |
| 80 mM | 0.1012 mL | 0.5059 mL | 1.0118 mL | 2.5295 mL | |
| 100 mM | 0.0809 mL | 0.4047 mL | 0.8095 mL | 2.0236 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Powered by Bioz