1. Anti-infection
  2. Parasite

Tafenoquine (Synonyms: WR 238605)

Cat. No.: HY-111529
Handling Instructions

Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent.

For research use only. We do not sell to patients.

Tafenoquine Chemical Structure

Tafenoquine Chemical Structure

CAS No. : 106635-80-7

Size Price Stock
5 mg USD 190 Get quote
10 mg USD 290 Get quote
50 mg USD 590 Get quote
100 mg USD 890 Get quote

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Other In-stock Forms of Tafenoquine:

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Other Forms of Tafenoquine:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent[1].

IC50 & Target

Anti-malarial[1]

In Vivo

Tafenoquine exhibits no anti-malarial activity in CYP 2D knock-out mice when dosed at their ED100 values (3 mg/kg) established in WT mice. Tafenoquine anti-malarial activity is partially restored in humanized/CYP 2D6 knock-in mice when tested at two times its ED100 (6 mg/kg)[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1575 mL 10.7877 mL 21.5754 mL
5 mM 0.4315 mL 2.1575 mL 4.3151 mL
10 mM 0.2158 mL 1.0788 mL 2.1575 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

463.49

Formula

C₂₄H₂₈F₃N₃O₃

CAS No.

106635-80-7

SMILES

CC1=CC(OC)=NC2=C1C(OC3=CC=CC(C(F)(F)F)=C3)=C(OC)C=C2NC(CCCN)C

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Tafenoquine
Cat. No.:
HY-111529
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Tafenoquine

Cat. No.: HY-111529