(±)-Alliin
Based on 3 publication(s) in Google Scholar
(±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.21%
- No. CAS: 17795-26-5
- Fòrmula: C6H11NO3S
- Peso molecular:177.22
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) (±)-Alliin
More
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Platelet | IC50 |
60 μM
Compound: 2, Alliin
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Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma at 1 mM by turbidimetric method
Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma at 1 mM by turbidimetric method
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[PMID: 8350088] |
| Platelet | IC50 |
60 μM
Compound: 2, Alliin
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Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma at 1 mM by turbidimetric method
Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma at 1 mM by turbidimetric method
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[PMID: 8350088] |
In Vitro
Molecular docking is used to assess the binding stability of various drugs with SARS-CoV-2 main protease (Mpro).(±)-Alliin is found to interact with SARS-CoV Mpro at Leu-167, Met-49 and Glu-166 with three H-bonds; for SARS-CoV-2 Mpro, the observed docking sites of (±)-Alliin are Cys-145, Met-49 and Glu-166 with three H-bonds[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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No. CAS 17795-26-5
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Appearance Solid
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Peso molecular 177.22
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Fòrmula C6H11NO3S
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Color White to light yellow
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SMILES
C=CCS(C[C@@H](C(O)=O)N)=O
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Synonyms
(±)-L-Alliin
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Nucleic Acids Res
COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics. [Abstract]2021 Jan 8;49(D1):D1113-D1121. PMID: 33166390 -
Sci Rep
Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease. [Abstract]2022 Jul 16;12(1):12197. PMID: 35842458 -
Iran J Pharm Res
Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes. [Abstract]2025 Oct 1;24(1):e164379. PMID: 41104235
Solvente y solubilidad
In Vitro:
H2O : 125 mg/mL (705.34 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 5.6427 mL | 28.2135 mL | 56.4270 mL | 141.0676 mL |
| 5 mM | 1.1285 mL | 5.6427 mL | 11.2854 mL | 28.2135 mL | |
| 10 mM | 0.5643 mL | 2.8214 mL | 5.6427 mL | 14.1068 mL | |
| 15 mM | 0.3762 mL | 1.8809 mL | 3.7618 mL | 9.4045 mL | |
| 20 mM | 0.2821 mL | 1.4107 mL | 2.8214 mL | 7.0534 mL | |
| 25 mM | 0.2257 mL | 1.1285 mL | 2.2571 mL | 5.6427 mL | |
| 30 mM | 0.1881 mL | 0.9405 mL | 1.8809 mL | 4.7023 mL | |
| 40 mM | 0.1411 mL | 0.7053 mL | 1.4107 mL | 3.5267 mL | |
| 50 mM | 0.1129 mL | 0.5643 mL | 1.1285 mL | 2.8214 mL | |
| 60 mM | 0.0940 mL | 0.4702 mL | 0.9405 mL | 2.3511 mL | |
| 80 mM | 0.0705 mL | 0.3527 mL | 0.7053 mL | 1.7633 mL | |
| 100 mM | 0.0564 mL | 0.2821 mL | 0.5643 mL | 1.4107 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
(±)-Alliin Related Classifications
HY-126085 Related Classifications
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