2. Others

Others

Others

Related Products

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There are a number of inhibitors, agonists, and antagonists which we cannot make precise classification because the research area is still unknown.

Others Related Products (73848):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W032915R
    5-Phenylvaleric acid (Standard) 2270-20-4
    5-Phenylvaleric acid (Standard) is an analytical standard for 5-Phenylvaleric acid (HY-W032915). This product is used for research and analytical applications. 5-Phenylvaleric acid (5-Phenylpentanoic acid) is a major metabolite produced by the gut microbiota during the metabolism of flavan-3-ols and can serve as a biomarker for flavan-3-ol intake. 5-Phenylvaleric acid can also be used as a raw material for the synthesis of polyhydroxyalkanoates.
    5-Phenylvaleric acid (Standard)
  • HY-14929
    Migalastat 108147-54-2 98%
    Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity.
    Migalastat
  • HY-44237
    Pomalidomide-CO-C-NH2 444289-11-6
    Pomalidomide-CO-C-NH2 (Compound 8) is a conjugate of an E3 ligand and a linker, which can be used for the synthesis of PROTACs, such as PROTAC B-Raf degrader 1 (HY-111758).
    Pomalidomide-CO-C-NH2
  • HY-D1388
    Cyanine3 NHS ester tetrafluoroborate 2632339-91-2 98%
    Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    Cyanine3 NHS ester tetrafluoroborate
  • HY-P0109
    (S,S)-Z-FA-FMK 105637-38-5 98%
    (S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. (S,S)-Z-FA-FMK blocks LPS-induced production of IL-1α and IL-1β. (S,S)-Z-FA-FMK can be used as a negative control for caspase-1 and caspase-2 inhibitors because it lacks an aspartic acid residue at the P1 position.
    (S,S)-Z-FA-FMK
  • HY-P3287
    UL75 (14-42)，Human herpesvirus 5 98%
    UL75 (14-42), Human herpesvirus 5, as a peptide, is a sequence of human herpesvirus 5.
    UL75 (14-42)，Human herpesvirus 5
  • HY-P4184
    Isotocin 550-21-0 98%
    Isotocin ((Ser4,Ile8)-Oxytocin) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development.
    Isotocin
  • HY-10550B
    Tariquidar dimesylate 625375-84-0 98%
    Tariquidar dimesylate (XR9576 dimesylate) is a P-glycoprotein (P-gp) inhibitor. Tariquidar dimesylate increases the concentration of the drug in the brain by binding to P-glycoprotein, preventing it from transporting the drug from inside to outside the brain. Tariquidar dimesylate can be used in the study of blood-brain barrier penetration and multidrug resistance.
    Tariquidar dimesylate
  • HY-111537
    rel-AZ5576 1333468-05-5 98%
    rel-AZ5576 is a selective CDK9 inhibitor with the activity of downregulating Mcl-1 and MYC mRNA transcription and protein expression in diffuse large B-cell lymphoma by inhibiting CDK9, promoting MYC protein turnover, reducing MYC phosphorylation on the stable Ser62 residue and downregulating MYC transcriptional targets, inhibiting the growth of diffuse large B-cell lymphoma cell lines in vitro and in vivo and independent of the cell origin.
    rel-AZ5576
  • HY-115525
    NBUMP 1348755-27-0 98%
    NBUMP is a 5-HT1A receptor ligand with a 5-HT1A receptor Ki of 0.1 nM, α1-adrenergic receptor Ki of 46 nM, and a 5-HT1A receptor-to-α1-adrenergic receptor selectivity ratio of 460.NBUMP binds to the 5-HT1A receptor with high affinity.NBUMP binds to the α1-adrenergic receptor with lower affinity.
    NBUMP
  • HY-115874
    BMS-753426 1004536-52-0 98%
    BMS-753426 is a potent and orally bioavailable antagonist of CCR2.
    BMS-753426
  • HY-144178
    HIF-2α-IN-6 2755401-07-9 98%
    HIF-2α-IN-6 (117) is a HIF-2α inhibitor.
    HIF-2α-IN-6
  • HY-148467
    METTL3-IN-1 2648257-77-4 98.07%
    METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor.
    METTL3-IN-1
  • HY-157998
    mG2N001 2760515-88-4 98%
    mG2N001 is a negative allosteric modulator (NAM) (IC50: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C]mG2N001 can be used in PET imaging. [11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images.
    mG2N001
  • HY-164077
    mPEG-PLGA 743423-15-6
    mPEG-PLGA is a mucus-penetrating polymer. mPEG-PLGA is a raw material to prepare nanomedicine.
    mPEG-PLGA
  • HY-171242
    LNK01004 2445500-24-1 98%
    LNK01004 is a JAK inhibitor with strong inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50:＜0.51 nM) and TYK2 (IC50: 1.0 nM) . LNK01004 can simultaneously inhibit multiple cytokine-induced p-STAT signaling pathways. LNK01004 can be used in the research of diseases such as atopic dermatitis.
    LNK01004
  • HY-175927
    ER ligand-13 2832871-49-3 98%
    ER ligand-13 is a ERα ligand and can be used for the synthesis of PROTACs, such as ERD-3111 (HY-149480).
    ER ligand-13
  • HY-184538
    Palbociclib-PEG3-NHBoc 2361493-13-0
    Palbociclib-PEG3-NHBoc is a target protein ligand-linker conjugate. Palbociclib-PEG3-NHBoc can be used for the synthesis of PROTAC BSJ-03-123 (HY-111556).
    Palbociclib-PEG3-NHBoc
  • HY-78036R
    Mesaconic acid (Standard) 498-24-8 98%
    Mesaconic acid (Standard) is the analytical standard of Mesaconic acid. This product is intended for research and analytical applications. Mesaconic acid is an active product that can be extracted from Saxifraga stolonifera. Mesaconic acid is used as a fire retardant and is a competitive inhibitor of fumarate reduction[1].
    Mesaconic acid (Standard)
  • HY-DY1018
    FITC-Dextran (MW 4000) (solution) 60842-46-8
    FITC-Dextran (MW 4000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.
    Solvent and Concentration: Sterile water: 2 mM
    FITC-Dextran (MW 4000) (solution)