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mG2N001

mG2N001 is a negative allosteric modulator (NAM) (IC50: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C]mG2N001 can be used in PET imaging. [11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images.

For research use only. We do not sell to patients.

  • CAS No.: 2760515-88-4
  • Formula: C18H19FN2O3
  • Molecular Weight:330.35
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • mG2N001 Chemical Structure
    mG2N001 Chemical Structure
CAS No.: 2760515-88-4
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All mGluR Isoforms

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  • mG2N001 Chemical Structure
    mG2N001 Chemical Structure
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  • mG2N001