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Cat. No.: HY-184538

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Palbociclib-PEG3-NHBoc

Palbociclib-PEG3-NHBoc is a target protein ligand-linker conjugate. Palbociclib-PEG3-NHBoc can be used for the synthesis of PROTAC BSJ-03-123 (HY-111556).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2361493-13-0
화학식: C₃₇H₅₄N₈O₇
분자량:722.87

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Palbociclib-PEG3-NHBoc Chemical Structure

CAS No.: 2361493-13-0

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Palbociclib-PEG3-NHBoc is a target protein ligand-linker conjugate. Palbociclib-PEG3-NHBoc can be used for the synthesis of PROTAC BSJ-03-123 (HY-111556)^[1].

In Vitro

Target protein ligand-linker conjugates combine a ligand for the target protein with a linker. When bound to an E3 ligase ligand, the conjugate becomes a PROTAC capable of inducing ubiquitination and subsequent degradation of the target protein.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 2361493-13-0
분자량 722.87
화학식 C₃₇H₅₄N₈O₇
SMILES

O=C(C(C(C)=O)=C1C)N(C2CCCC2)C3=C1C=NC(NC4=CC=C(N5CCN(CCOCCOCCOCCNC(OC(C)(C)C)=O)CC5)C=N4)=N3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Jiang B, et al. Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6. Angew Chem Int Ed Engl. 2019 May 6;58(19):6321-6326. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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