2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125048
    Racemomycin B
    		Inhibitor
    Racemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.
    Racemomycin B
  • HY-B0537A
    Pentamidine dihydrochloride
    		Inhibitor
    Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
    Pentamidine dihydrochloride
  • HY-172229
    NBTI 5463
    		Inhibitor
    NBTI 5463 is a bacterial type II topoisomerases (topoisomerase II) inhibitor with antibacterial activity. NBTI 5463 inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. NBTI 5463 binds to topoisomerase II to prevent DNA cleavage and religation, inhibiting bacterial DNA replication and transcription. NBTI 5463 is promising for research of Gram-negative bacterial infection.
    NBTI 5463
  • HY-N14680
    Glysperin C
    		Inhibitor
    Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity.
    Glysperin C
  • HY-N14548
    Cryptosporiopsin
    		Inhibitor
    Cryptosporiopsin can be isolated from the strain of Cryptosporiopsis sp. and Sporormia affinis. Cryptosporiopsin has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. Cryptosporiopsin also has certain activity against gram-positive bacteria and negative bacteria.
    Cryptosporiopsin
  • HY-B1773AS1
    Sodium propionate-13C-1
    		Inhibitor
    Sodium propionate-13C-1 is the 13C-labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
    Sodium propionate-<sup>13</sup>C-1
  • HY-N13973
    Baumycin A1
    		Inhibitor
    Baumycin A1 is an antitumor antibiotic.
    Baumycin A1
  • HY-182444
    Cefaloram
    		Inhibitor
    Cefaloram is a cephalosporin antibiotic, but it is inactive against clinical cystic fibrosis isolates of Pseudomonas aeruginosa (MIC50 > 128 μg/mL).
    Cefaloram
  • HY-N14396
    Sannamycin F
    		Inhibitor
    Sannamycin F is an aminoglycoside antibiotic. Sannamycin F has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.
    Sannamycin F
  • HY-159118
    PC-Qz1
    		Inhibitor
    PC-Qz1 is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor with an IC50 of 470 nM. PC-Qz1 has antibacterial activity.
    PC-Qz1
  • HY-N14691
    Platenomycin C3
    		Inhibitor
    Platenomycin C3 is a macrolide antibiotic with anti-Gram-positive bacteria effects.
    Platenomycin C3
  • HY-137956
    Previridicatumtoxin
    		Inhibitor
    Previridicatumtoxin is a fungal metabolite with antibacterial and anticancer activities. Previridicatumtoxin can be extracted from P. aethiopicum and utilized in research related to cancer as well as infections.
    Previridicatumtoxin
  • HY-175795
    Tyrosinase activator-1
    		Inhibitor
    Tyrosinase activator-1 (Compound 7A) is a Tyrosinase activator. Tyrosinase activator-1 significant antibacterial activity against gram-positive bacteria, such as MRSA, Staphylococcus aureus ATCC653 and Enterococcus faecium with MICs of 12.5-20  μM. Tyrosinase activator-1 activates tyrosinase by competitively occupying the binding site of L-DOPA on the surface of tyrosinase without interfering with the substrate binding at the active center. Tyrosinase activator-1 can be used for bacterial infections and antibiotics development research.
    Tyrosinase activator-1
  • HY-N14840
    1-Hydroxysulfurmycin A
    		Inhibitor
    1-Hydroxysulfurmycin A is an anthracycline antibiotic. 1-Hydroxysulfurmycin A has anti-Gram-positive bacteria and anti-tumor cell activity.
    1-Hydroxysulfurmycin A
  • HY-B2170B
    Octenidine (saccharin)
    		Inhibitor
    Octenidine saccharin is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine saccharin can inhibit the expression of biofilm genes and destroy the formation of biofilms.
    Octenidine (saccharin)
  • HY-B0210R
    Cefoperazone (Standard)
    		Inhibitor
    Cefoperazone (Standard) is the analytical standard of Cefoperazone. This product is intended for research and analytical applications. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.
    Cefoperazone (Standard)
  • HY-B0706AR
    Flomoxef sodium (Standard)
    		Inhibitor
    Flomoxef (sodium) (Standard) is the analytical standard of Flomoxef (sodium). This product is intended for research and analytical applications. Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria.
    Flomoxef sodium (Standard)
  • HY-N14093
    Aspulvinone H
    		Inhibitor
    Aspulvinone H is an orally active inhibitor of AChE, pancreatic lipase, glutamic-oxaloacetic transaminase 1, and α-glucosidase, with IC50 values of 25.95 μM, 47.06 μM, 5.91/6.91 μM, and 4.6 μM, respectively. It has a Ka of 2.14 μM against GOT1 and a Ki of 6.58 μM against α-glucosidase. Aspulvinone H inhibits cancer cell proliferation, interferes with glutamine metabolism, elevates ROS levels, and induces cell apoptosis and S-phase arrest. Aspulvinone H exhibits antibacterial activity against Staphylococcus aureus. Aspulvinone H inhibits the growth of pancreatic ductal adenocarcinoma xenografts. Aspulvinone H reduces postprandial blood glucose in mice. Aspulvinone H can be used in research related to pancreatic ductal adenocarcinoma, diabetes, and Staphylococcus aureus infection.
    Aspulvinone H
  • HY-N15030
    Diatretyne Ⅰ
    		Inhibitor
    Diatretyne I (Diatretyne amide) has weak anti-Gram-positive bacterial activity.
    Diatretyne Ⅰ
  • HY-170937
    Urease-IN-20
    		Inhibitor
    Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori). Urease-IN-20 inhibits H. pylori with an IC50 of 0.14 μM. Urease-IN-20 reduces cell Apoptosis and decreases ROS and γH2AX in GES-1 cells infected with H. pylori. Urease-IN-20 exhibits significant gastric mucosal protective effects. Urease-IN-20 shows the potential for H. pylori research.
    Urease-IN-20
Cat. No. Product Name / Synonyms Application Reactivity