NBTI 5463

NBTI 5463 is a bacterial type II topoisomerases (topoisomerase II) inhibitor with antibacterial activity. NBTI 5463 inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. NBTI 5463 binds to topoisomerase II to prevent DNA cleavage and religation, inhibiting bacterial DNA replication and transcription. NBTI 5463 is promising for research of Gram-negative bacterial infection.

For research use only. We do not sell to patients.

  • CAS No.: 1227303-03-8
  • Formula: C25H30N6O4
  • Molecular Weight:478.54
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Topoisomerase Isoforms

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