Cefaloram
Cefaloram is a cephalosporin antibiotic, but it is inactive against clinical cystic fibrosis isolates of Pseudomonas aeruginosa (MIC50 > 128 μg/mL).
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- CAS. Nr.: 859-07-4
- Formel: C18H18N2O6S
- Molecular Weight:390.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
Cefaloram (overnight) exhibits no antibacterial activity against the *Pseudomonas aeruginosa* reference strain PAO1 and 10 cystic fibrosis clinical isolates (MIC > 128 μg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 859-07-4
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Molecular Weight 390.41
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Formel C18H18N2O6S
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SMILES
OC(C1=C(COC(C)=O)CS[C@@]([C@@H]2NC(CC3=CC=CC=C3)=O)([H])N1C2=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1].
Rineh A, et al. Discovery of Cephalosporin-3'-Diazeniumdiolates That Show Dual Antibacterial and Antibiofilm Effects against Pseudomonas aeruginosa Clinical Cystic Fibrosis Isolates and Efficacy in a Murine Respiratory Infection Model. ACS Infect Dis. 2020 Jun 12;6(6):1460-1479.
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)