2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-66011S
    rac cis-Moxifloxacin-d4 hydrochloride
    		99.78%
    rac cis-Moxifloxacin-d4 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    rac cis-Moxifloxacin-d<sub>4</sub> hydrochloride
  • HY-N5162
    Arborcandin C
    Arborcandin C is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC50 values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida.
    Arborcandin C
  • HY-N7121R
    Erythromycin estolate (Standard)
    Erythromycin estolate (Standard) is the analytical standard of Erythromycin estolate. This product is intended for research and analytical applications. Erythromycin estolate is the Erythromycin (HY-B0220) derivative, is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport.
    Erythromycin estolate (Standard)
  • HY-N0716AR
    Berberine hemisulfate (Standard)
    Berberine (hemisulfate) (Standard) is the analytical standard of Berberine (hemisulfate). This product is intended for research and analytical applications. Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity.
    Berberine hemisulfate (Standard)
  • HY-B0035AR
    Sulfamethazine sodium (Standard)
    Sulfamethazine (sodium) (Standard) is the analytical standard of Sulfamethazine (sodium). This product is intended for research and analytical applications. Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 μg/kg[1][2].
    Sulfamethazine sodium (Standard)
  • HY-N19795
    Desferritriacetylfusigen
    Desferritriacetylfusigen is a desferrisideramine antibiotic found in Aspergillus deflectus and bacterial growth inhibitor. Desferritriacetylfusigen induces strong iron deficiency in sensitive bacteria to block growth, with activity abolished by iron (III) addition. Desferritriacetylfusigen exhibits medium-dependent bacterial growth inhibition, with no or weak activity against yeasts and fungi. can be used for research on bacterial infection.
    Desferritriacetylfusigen
  • HY-W353258R
    Moxifloxacin hydrochloride monohydrate (Standard)
    Moxifloxacin hydrochloride (BAY 12-8039) monohydrate (Standard) is the analytical standard of Moxifloxacin hydrochloride monohydrate. This product is intended for research and analytical applications. Moxifloxacin hydrochloride monohydrate is a blood-brain barrier-permeable, orally active topoisomerase II/IV inhibitor and a fluoroquinolone antibiotic. Moxifloxacin hydrochloride monohydrate disrupts bacterial DNA replication, transcription, repair and chromosome segregation processes. Moxifloxacin hydrochloride monohydrate exhibits activity against Gram-positive bacteria, Gram-negative bacteria, anaerobes, atypical pathogens, drug-resistant respiratory pathogens, Mycobacterium tuberculosis, mycoplasmas and Ureaplasma urealyticum.
    Moxifloxacin hydrochloride monohydrate (Standard)
  • HY-B0905AR
    Tilmicosin phosphate (Standard)
    Tilmicosin (phosphate) (Standard) is the analytical standard of Tilmicosin (phosphate). This product is intended for research and analytical applications. Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects.
    Tilmicosin phosphate (Standard)
  • HY-B1241A
    Dihydrostreptomycin
    Dihydrostreptomycin (DHSM) is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss.
    Dihydrostreptomycin
  • HY-W012444S
    Glyceryl 1-monooctanoate-d15
    Glyceryl 1-monooctanoate-d15 is the deuterium labeled Glyceryl 1-monooctanoate (HY-W012444). Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria.
    Glyceryl 1-monooctanoate-d<sub>15</sub>
  • HY-136817
    Nanaomycin αA
    Nanaomycin αA (OM173-αA) is an antibiotic with antimicrobial activity. Nanaomycin αA can be isolated from a fermentation broth of Streptomyces hebeiensis derived from lichen.
    Nanaomycin αA
  • HY-10211S
    Tanespimycin-d5
    Tanespimycin-d5 (17-AAG-d5; NSC 330507-d5; CP 127374-d5) is the deuterium labeled Tanespimycin (HY-10211). Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression.
    Tanespimycin-d<sub>5</sub>
  • HY-B0439R
    Sulfadoxine (Standard)
    Sulfadoxine (Standard) is the analytical standard of Sulfadoxine. This product is intended for research and analytical applications. Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other agents, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.
    Sulfadoxine (Standard)
  • HY-109855
    CP-67015
    CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects.
    CP-67015
  • HY-121709
    4-Aminopteroylaspartic acid
    4-Aminopteroylaspartic acid (Amino-An-Fol) inhibits the growth of psittacosis virus (6BC) in tissue cultures at concentrations which were not toxic. 4-Aminopteroylaspartic acid inhibts growth of meningopneumonitis virus in embryonated eggs or tissue culture.
    4-Aminopteroylaspartic acid
  • HY-136295
    Quinaldopeptin
    Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells.
    Quinaldopeptin
  • HY-15460R
    CHIR-090 (Standard)
    CHIR-090 (Standard) is the analytical standard of CHIR-090. This product is intended for research and analytical applications. CHIR-090 is a potent, slow, tight-binding inhibitor of the LpxC deacetylase. It binds to E. coli LpxC with a Ki of 4.0 nM. CHIR-090 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CHIR-090 (Standard)
  • HY-126606
    Isochlortetracycline
    Isochlortetracycline is an inactive alkaline degradation product of the Chlortetracycline (HY-B1327A) (broad-spectrum antibiotic).
    Isochlortetracycline
  • HY-100381R
    Nigericin sodium salt (Standard)
    Nigericin (sodium salt) (Standard) is the analytical standard of Nigericin (sodium salt). This product is intended for research and analytical applications. Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1/GSDMD in TNBC.
    Nigericin sodium salt (Standard)
  • HY-114900
    BB-3497
    BB-3497 is a potent, orally active and selective peptide deformylase (PDF) inhibitor. BB-3497 is highly selective for PDF (IC50 = 7 nM for E. coli PDF.Ni) over the other mammalian metalloenzymes (MMP-1/2/3/7 and enkephalinase). BB-3497 exhibits potent activity against gram-positive bacteria and some gram-negative pathogens. BB-3497 protects mice from infection in systemic models of Staphylococeus aureus. BB-3497 can be used for anti-bacterial infection research.
    BB-3497
Antibiotic Isoform Comparison

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