2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0449R
    Methacycline hydrochloride (Standard)
    Methacycline (hydrochloride) (Standard) is the analytical standard of Methacycline (hydrochloride). This product is intended for research and analytical applications. Methacycline hydrochloride is a tetracycline antibiotic and can inhibits bacterial protein synthesis. Methacycline hydrochloride is a potent epithelial-mesenchymal transition (EMT) inhibitor. Methacycline hydrochloride blocks EMT in vitro and fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline hydrochloride is an antimicrobial and has the potential for pulmonary fibrosis.
    Methacycline hydrochloride (Standard)
  • HY-B0147B
    Pefloxacin mesylate dihydrate
    		98.11%
    Pefloxacin (Pefloxacinium) mesylate dihydrate is a broad spectrum antibiotic. Pefloxacin mesylate dihydrate blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate dihydrate inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin mesylate dihydrate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate dihydrate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate dihydrate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate dihydrate can be used for infection studies.
    Pefloxacin mesylate dihydrate
  • HY-177996
    Clindamycin palmitate
    Clindamycin palmitate is an antibacterial agent. Clindamycin palmitate is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin.
    Clindamycin palmitate
  • HY-N5194
    Lipohexin
    Lipohexin is a peptide antibiotic. Lipohexin has anti-Gram-positive bacterial effect. Lipohexin had competitive inhibitory effect on human placental proline endopeptidase with an IC50 of 3.5 μM. Lipohexin inhibits the proline endopeptidase from the Flavobacterium meningoseptiu with an IC50 of 25 μM.
    Lipohexin
  • HY-N13987
    Arylomycin B7
    Arylomycin B7 is a lipohexapeptide antibiotic against Gram-positive bacteria.
    Arylomycin B7
  • HY-N14559
    Dynemicin O
    Dynemicin O is an antibiotic and has strong anti-Gram-positive bacterial activity.
    Dynemicin O
  • HY-136439R
    4-Epianhydrotetracycline hydrochloride (Standard)
    4-Epianhydrotetracycline hydrochloride (Standard) is the analytical standard of 4-Epianhydrotetracycline hydrochloride. This product is intended for research and analytical applications. 4-Epianhydrotetracycline hydrochloride is a major intermediate product of Tetracycline (HY-A0107). 4-Epianhydrotetracycline hydrochloride shows lethal effects and induces cell apoptosis of zebrafish embryos. 4-Epianhydrotetracycline hydrochloride inhibits Shewanella, E. coli and P. aeruginosa with MIC values of 2, 1 and 64 mg/L, respectively.
    4-Epianhydrotetracycline hydrochloride (Standard)
  • HY-N14850
    Napsamycin B
    Napsamycin B is an antibiotic. Napsamycin B has antibacterial activity against Pseudomonas aeruginosa and other pseudomonas, but has weak antibacterial activity against other Gram-positive and negative bacteria.
    Napsamycin B
  • HY-W777995
    Clindamycin B
    Clindamycin B is a derivative of Clindamycin (HY-B1455).
    Clindamycin B
  • HY-N15127
    3-O-Demethyl-2'-N-glylfortimicin B
    3-O-Demethyl-2'-N-glylfortimicin B is an aminoglycoside antibiotic.
    3-O-Demethyl-2'-N-glylfortimicin B
  • HY-N5168
    Argimicin B
    Argimicin B is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin B exhibits algicidal activity against a variety of toxic cyanobacteria with MIC of low micromolar levels.
    Argimicin B
  • HY-N14854
    Dynemicin P
    Dynemicin P is an antibiotic.
    Dynemicin P
  • HY-113557
    DNAC-1
    DNAC-1 is a potent antibacterial agent. DNAC-1 enhances β-lactam activity against Gram positive and Gram negative pathogens.
    DNAC-1
  • HY-B0519AR
    Tylosin (Standard)
    Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle.
    Tylosin (Standard)
  • HY-17422D
    Acyclovir hydrochloride
    Acyclovir (Aciclovir) hydrochloride is a potent, orally active antiviral agent. Acyclovir hydrochloride has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir hydrochloride induces cell cycle perturbation and apoptosis. Acyclovir hydrochloride prevents bacterial infections during induction therapy for acute leukaemia.
    Acyclovir hydrochloride
  • HY-N15125
    1-Deamino-1-hydroxygentamicin C2
    1-Deamino-1-hydroxygentamicin C2 (Antibiotic SU-1) is an aminoglycotone antibiotic. 1-Deamino-1-hydroxygentamicin C2 has the activity against Gram-positive and Gram-negative bacteria.
    1-Deamino-1-hydroxygentamicin C2
  • HY-B0323R
    Sulfisoxazole (Standard)
    Sulfisoxazole (Standard) is the analytical standard of Sulfisoxazole. This product is intended for research and analytical applications. Sulfisoxazole (Sulfafurazole) is an orally active endothelin receptor antagonist with IC50 values of 0.60 μM and 22 μM against endothelin receptor A and endothelin receptor B, respectively. Sulfisoxazole is a sulfonamide antibacterial agent with an oxazole substituent. Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A.
    Sulfisoxazole (Standard)
  • HY-N14995
    Frenolicin
    Frenolicin is an antibiotic with antibacterial activity. Frenolicin also exhibits cytotoxicity against tumor cells.
    Frenolicin
  • HY-14865CR
    Omadacycline hydrochloride (Standard)
    Omadacycline (hydrochloride) (Standard) is the analytical standard of Omadacycline (hydrochloride). This product is intended for research and analytical applications. Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].
    Omadacycline hydrochloride (Standard)
  • HY-N14799
    Mycobacillin
    Mycobacillin is a peptide antibiotic with anti-antifungal activity.
    Mycobacillin
Antibiotic Isoform Comparison

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