1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N15071
    23-De(mycinosyloxy)tylosin
    23-De(mycinosyloxy)tylosin is a macrolide antibiotic. 23-De(mycinosyloxy)tylosin has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria and mycoplasma activity.
    23-De(mycinosyloxy)tylosin
  • HY-13553S1
    Anidulafungin-13C6
    Anidulafungin-13C6 (LY303366-13C6) is 13C labeled Anidulafungin. Anidulafungin is a new semisynthetic echinocandin with antifungal potency.
    Anidulafungin-<sup>13</sup>C<sub>6</sub>
  • HY-N14202
    Maridomycin V
    Maridomycin V is a macrolide antibiotic. Maridomycin Vhas the activity against Gram-positive bacteria and mycoplasma. Maridomycin V has the effect of protecting Gram-positive bacterial infection mice.
    Maridomycin V
  • HY-B0368B
    D-Captopril
    Activator
    D-Captopril is a NDM-1 inhibitor and a competitive BlaB inhibitor, with an IC50 value of 21.8 µM against NDM-1 and a Ki of 70-100 µM against BlaB. D-Captopril synergistically reduces the minimum inhibitory concentration of Meropenem (HY-13678) against NDM-1-expressing bacteria. D-Captopril binds to BcII via its thiolate sulfur atom and carboxylate group, altering metal ion occupancy and modulating Cd2+ binding affinity. D-Captopril can be used in the research of neonatal meningitis, sepsis and bacterial infections.
    D-Captopril
  • HY-124508
    Lambertellin
    Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.
    Lambertellin
  • HY-N14898
    Oudermansin B
    Oudermansin B is an antibiotic. Oudermansin B acts on fungi to inhibit protein, RNA and DNA synthesis.
    Oudermansin B
  • HY-B0465R
    Oxacillin sodium monohydrate (Standard)
    Oxacillin (sodium monohydrate) (Standard) is the analytical standard of Oxacillin (sodium monohydrate). This product is intended for research and analytical applications. Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study.
    Oxacillin sodium monohydrate (Standard)
  • HY-N14674
    Permetin A
    Permetin A is a peptide antibiotic. Permetin A has anti-Gram-negative bacteria, Gram-positive bacteria and anaerobic bacteria activity.
    Permetin A
  • HY-B1374S
    ent-Florfenicol-d3
    ent-Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
    ent-Florfenicol-d<sub>3</sub>
  • HY-182535
    Tuberactinomycin-O
    Tuberactinomycin-O is a peptide antibiotic belonging to the tuberactinomycin family. Tuberactinomycin-O inhibits the growth of various bacteria, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Mycobacterium ATCC 607. Tuberactinomycin-O exhibits acute toxicity in male mice when administered intravenously. Tuberactinomycin-O can be used in the research of tuberculosis.
    Tuberactinomycin-O
  • HY-B0024R
    Prulifloxacin (Standard)
    Prulifloxacin (Standard) is the analytical standard of Prulifloxacin. This product is intended for research and analytical applications. Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis.
    Prulifloxacin (Standard)
  • HY-121206R
    (-)-Isopulegol (Standard)
    (-)-Isopulegol (Standard) is the analytical standard of (-)-Isopulegol. This product is intended for research and analytical applications. (-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research.
    (-)-Isopulegol (Standard)
  • HY-N15129
    7β,8β-2′,3′-Diepoxyroridin H
    7β,8β-2′,3′-Diepoxyroridin H is an antibiotic with anti-Gram-positive and negative bacteria activity.
    7β,8β-2′,3′-Diepoxyroridin H
  • HY-125650A
    Pseudouridimycin TFA
    Pseudouridimycin (PUM) TFA is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC50 of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin TFA is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin TFA inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis.
    Pseudouridimycin TFA
  • HY-A0153R
    Cephapirin (Standard)
    Cephapirin (Standard) is the analytical standard of Cephapirin. This product is intended for research and analytical applications. Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity.
    Cephapirin (Standard)
  • HY-101136
    Dealanylascamycin
    Dealanylascamycin (AT-265) (Compound 2) is a nucleoside antibiotic. AT 265 is a carbonic anhydrase (CA) inhibitor, with Ki values of 167, 65.2, 234, and 143 nM for hCA I, hCA II, hCA IV, and hCA IX respectively. Dealanylascamycin is the active form of Ascamycin (HY-121071). Dealanylascamycin exhibits broad-spectrum antibacterial activity and is effective against pathogenic bacteria such as Xanthomonas citri (MIC = 0.4 μg/mL). Dealanylascamycin has high cytotoxicity.
    Dealanylascamycin
  • HY-N15028
    Depsidomycin
    Depsidomycin is an immunomodulatory antibiotic with immunosuppressive activity that can be isolated from the culture broth of Streptomyces lavendofoliae MI951-62F2. Depsidomycin primarily exhibits antibacterial activity against Gram-positive bacteria.
    Depsidomycin
  • HY-N14334
    Halomicin B
    Halomicin B is an ansamycin antibiotic. Halomicin B has activity against Gram-positive and Gram-negative bacteria (individual).
    Halomicin B
  • HY-P5725
    Aurein 2.1
    Aurein 2.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria aurea and Litoria raniformis.
    Aurein 2.1
  • HY-N14067
    Cytosaminomycin A
    Cytosaminomycin A is an antibiotic with anticoccidial and antibacterial activities.
    Cytosaminomycin A

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