Tuberactinomycin-O 

Tuberactinomycin-O is a peptide antibiotic belonging to the tuberactinomycin family. Tuberactinomycin-O inhibits the growth of various bacteria, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Mycobacterium ATCC 607. Tuberactinomycin-O exhibits acute toxicity in male mice when administered intravenously. Tuberactinomycin-O can be used in the research of tuberculosis^[1].

Tuberactinomycin-O (24 h) inhibits the growth of multiple bacterial strains in vitro, with the highest potency against Bacillus subtilis PCI 219 (MIC 3.2 mcg/mL) and Mycobacterium ATCC 607 (MIC 6.3 mcg/mL), and the lowest potency against Staphylococcus aureus FDA 209 P and Sarcina lutea ATCC 1001 (MIC 100 mcg/mL)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tuberactinomycin-O (370 mg/kg; i.v.; single dose) exhibits an acute intravenous LD₅₀ of 370 mg/kg in male mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

669.69

C₂₅H₄₃N₁₃O₉

33137-73-4

O=C1[C@](NC(/C(NC([C@@H](NC([C@@H](NC([C@H](CN1)NC(C[C@@H](N)CCCN)=O)=O)CO)=O)CO)=O)=C/NC(N)=O)=O)([H])[C@]2([H])NC(N)=NCC2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. IZUMI R, et al. Studies on tuberactinomycin. III Isolation and characterization of two minor components, tuberactinomycin B and tuberactinomycin O. The Journal of Antibiotics, 1972, 25(4): 201-207.