Anidulafungin-13C6
Anidulafungin-13C6 (LY303366-13C6) is 13C labeled Anidulafungin. Anidulafungin is a new semisynthetic echinocandin with antifungal potency.
For research use only. We do not sell to patients.
- Formula: C5213C6H73N7O17
- Molecular Weight:1146.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 166663-25-8
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Molecular Weight 1146.19
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Formula C5213C6H73N7O17
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SMILES
O[C@@H]1C[C@@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@@H]([C@@H](C[C@@H](C(N[C@H](C3=O)[C@@H](C)O)=O)NC([13C]4=[13CH][13CH]=[13C]([13CH]=[13CH]4)C5=CC=C(C=C5)C6=CC=C(C=C6)OCCCCC)=O)O)O)=O)[C@H]([C@H](C2)C)O)=O)[C@H](O)C)=O)[C@@H]([C@H](C7=CC=C(C=C7)O)O)O)=O)N3C1
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Synonyms
LY303366-13C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Zhanel GG, et al. In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species. Antimicrob Agents Chemother. 1997 Apr;41(4):863-5 [Content Brief]
[3]. Locke JB, et al. Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6100-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)