1. Metabolic Enzyme/Protease Immunology/Inflammation
  2. Endogenous Metabolite COX
  3. Cholesteryl eicosapentaenoate

Cholesteryl eicosapentaenoate  (Synonyms: CE(20:5(5Z,8Z,11Z,14Z,17Z))

Cat. No.: HY-113463 Purity: 99.9%
Handling Instructions Technical Support

Cholesteryl eicosapentaenoate (CE(20:5(5Z,8Z,11Z,14Z,17Z)), a cholesteryl ester, is a COX-1 and COX-2 inhibitor with IC50 values of 14.6 μg/mL and 17.3 μg/mL, respectively. Cholesteryl eicosapentaenoate shows strong anti-inflammatory and antioxidant activities.

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Cholesteryl eicosapentaenoate

Cholesteryl eicosapentaenoate 화학구조

CAS No. : 74892-97-0

사이즈 가격 재고 수량
Solution
1 mg (15 mM * 100 μL in Chloroform) 해외재고보유
Liquid
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5 mg 견적 받기
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  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Cholesteryl eicosapentaenoate (CE(20:5(5Z,8Z,11Z,14Z,17Z)), a cholesteryl ester, is a COX-1 and COX-2 inhibitor with IC50 values of 14.6 μg/mL and 17.3 μg/mL, respectively. Cholesteryl eicosapentaenoate shows strong anti-inflammatory and antioxidant activities[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

COX-1

14.6 μg/mL (IC50)

COX-2

17.3 μg/mL (IC50)

In Vitro

At 25 μg/mL concentration, Cholesteryl eicosapentaenoate inhibits lipid peroxidation (LPO) by 72%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

671.09

화학식

C47H74O2

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@@H](CCCC(C)C)C)CC[C@@]4([H])[C@]3([H])CC=C2C1)=O

Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Solution, -20°C, 2 years

순도&문서

Purity: 99.9%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Cholesteryl eicosapentaenoate
Cat. No.:
HY-113463
수량:
MCE Japan Authorized Agent: