1. Anti-infection
  2. Antibiotic Bacterial
  3. Clovibactin

Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors.

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Clovibactin

Clovibactin Estructura química

No. CAS : 2247194-77-8

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50 mg   Obtener un presupuesto  
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250 mg   Obtener un presupuesto  

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Descripciòn

Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors[1].

In Vitro

Clovibactin TFA inhibits Staphylococcus strains with MICs of 0.125-2 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Clovibactin TFA (20 mg/kg, iv, single dose) exhibits a pharmacokinetic profil with a Cmax of 219.3 μg/mL, an AUCto last of 31.9 μg·h/mL, t1/2 of 2 h, CL of 9.4 mL/kg/min and a Vdss of 189.8 mL/kg in mice model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

903.08

Fòrmula

C43H70N10O11

No. CAS
Sequence

Phe-{d-Leu}-{d-Lys}-Ser-{Hyn}-Ala-Leu-Leu (Cyclic ester: Hyn5-Leu8)

Sequence Shortening

F-{d-Leu}-{d-Lys}-S-{Hyn}-ALL (Cyclic ester: Hyn5-Leu8)

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Clovibactin
Cat. No.:
HY-P10027
Cantidad:
MCE Japan Authorized Agent: