2. GPCR/G Protein Neuronal Signaling
  3. Adenosine Receptor Monoamine Oxidase
  4. (E)-8-(3-Chlorostyryl)caffeine

(E)-8-(3-Chlorostyryl)caffeine  (Synonyms: (E)-CSC)

製品番号: HY-103164 純度: 99.4%
COA 取扱説明書 Technical Support

(E)-8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist. (E)-8-(3-Chlorostyryl)caffeine inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM by a pathway that is independent of its actions on the A2A receptor. (E)-8-(3-Chlorostyryl)caffeine has the potential for Parkinson's disease research.

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(E)-8-(3-Chlorostyryl)caffeine

(E)-8-(3-Chlorostyryl)caffeine 構造式

CAS 番号 : 147700-11-6

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 204 在庫あり
Solution
10 mM * 1 mL in DMSO USD 204 在庫あり
Solid
5 mg $186 在庫あり
10 mg $298 在庫あり
25 mg $585 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Other Forms of (E)-8-(3-Chlorostyryl)caffeine:

(E)-8-(3-Chlorostyryl)caffeine 関連抗体

Top Publications Citing Use of Products

Adenosine Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

Monoamine Oxidase アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
MAO-A MAO-B

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製品説明

(E)-8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist. (E)-8-(3-Chlorostyryl)caffeine inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM by a pathway that is independent of its actions on the A2A receptor. (E)-8-(3-Chlorostyryl)caffeine has the potential for Parkinson's disease research[1].

IC50 & Target[1]

A2AR

 

MAO-B

70 nM (Ki)

分子量

330.77

分子式

C16H15ClN4O2
CAS 番号
Appearance

Solid

Color

Off-white to light yellow

SMILES

CN1C2=C(N(C(N(C2=O)C)=O)C)N=C1/C=C/C3=CC(Cl)=CC=C3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外: 

DMSO : 8.27 mg/mL (25.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0232 mL 15.1162 mL 30.2325 mL
5 mM 0.6046 mL 3.0232 mL 6.0465 mL
10 mM 0.3023 mL 1.5116 mL 3.0232 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.4%

COA (248 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0232 mL 15.1162 mL 30.2325 mL 75.5812 mL
5 mM 0.6046 mL 3.0232 mL 6.0465 mL 15.1162 mL
10 mM 0.3023 mL 1.5116 mL 3.0232 mL 7.5581 mL
15 mM 0.2015 mL 1.0077 mL 2.0155 mL 5.0387 mL
20 mM 0.1512 mL 0.7558 mL 1.5116 mL 3.7791 mL
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(E)-8-(3-Chlorostyryl)caffeine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-8-(3-Chlorostyryl)caffeine147700-11-6(E)-CSCAdenosine ReceptorMonoamine OxidaseP1 receptorMAOadenosine A2A receptormonoamine oxidase BMAO-BParkinson's diseaseInhibitorinhibitorinhibit

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製品名:
(E)-8-(3-Chlorostyryl)caffeine
製品番号:
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