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8-(3-Chlorostyryl)caffeine

(Synonyms: CSC)
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Based on 1 publication(s) in Google Scholar

8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity.

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  • CAS No.: 148589-13-3
  • Formula: C16H15ClN4O2
  • Molecular Weight:330.77
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 8-(3-Chlorostyryl)caffeine Chemical Structure
    8-(3-Chlorostyryl)caffeine Chemical Structure
CAS No.: 148589-13-3
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  • 8-(3-Chlorostyryl)caffeine Chemical Structure
    8-(3-Chlorostyryl)caffeine Chemical Structure
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  • 8-(3-Chlorostyryl)caffeine