2. GPCR/G Protein Cytoskeleton
  3. Endothelin Receptor Integrin
  4. Endothelin-3, human, mouse, rabbit, rat TFA

Endothelin-3, human, mouse, rabbit, rat TFA  (Synonyms: Endothelin 3 (Rat,Human) TFA)

Art. -Nr.: HY-P0204A Reinheit: 99.57%
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Endothelin-3, human, mouse, rabbit, rat TFA (Endothelin 3 (Rat,Human) TFA) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat TFA stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat TFA plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat TFA acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat TFA can be used in studies related to distal aganglionosis.

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Endothelin-3, human, mouse, rabbit, rat TFA

Endothelin-3, human, mouse, rabbit, rat TFA Chemische Struktur

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Based on 1 publication(s) in Google Scholar

Other Forms of Endothelin-3, human, mouse, rabbit, rat TFA:

Endothelin-3, human, mouse, rabbit, rat TFA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Endothelin-3, human, mouse, rabbit, rat TFA

Alle Endothelin Receptor Isoform-spezifische Produkte anzeigen:

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ETA ETB

Alle Integrin Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Beschreibung

Endothelin-3, human, mouse, rabbit, rat TFA (Endothelin 3 (Rat,Human) TFA) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat TFA stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat TFA plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat TFA acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat TFA can be used in studies related to distal aganglionosis[1].

IC50 & Target[1]

β1-integrin

 

In Vitro

Endothelin-3, human, mouse, rabbit, rat (100 nM-1 μM) TFA significantly enhances the adhesion capacity of mouse E12.5 YFP-labeled enteric neural crest cells cultured on fibronectin, increases the number and size of focal adhesions, and promotes the formation of lamellipodia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Endothelin-3, human, mouse, rabbit, rat TFA Related Antibodies
Molekulargewicht

2757.07 (free base)

Formel

C123H169F3N26O35S4.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
Sequence Shortening

CTCFTYKDKECVYYCHLDIIW(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Reinheit & Dokumentation

Purity: 99.57%

SDS (252 KB)

COA (259 KB) RP-HPLC (290 KB) MS (69 KB) Elemental Analysis Report (119 KB)

Handling Instructions (2659 KB)
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Endothelin-3, human, mouse, rabbit, rat TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Endothelin-3, human, mouse, rabbit, ratEndothelin 3 (Rat,Human)Endothelin ReceptorIntegrinEndothelin receptor type Bdistal aganglionosisenteric nervous systemARP2/3-WAVE2 pathwayenteric neural crest cellfocal adhesionslamellipodia formationβ1-integrinextracellular matrix componentsactin cytoskeleton remodellingInhibitorinhibitorinhibit

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