Folic acid-¹³C₅,¹⁵N  (Synonyms: Vitamin B9-¹³C₅,¹⁵N; Vitamin M-¹³C₅,¹⁵N)

Folic acid-¹⁵N,¹³C₅ is the ¹³C₅ and ¹⁵N labeled Folic acid (HY-16637)^[1].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
Folic acid plays a critical role in the prevention of chromosome breakage and hypomethylation of DNA^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

447.35

C₁₄¹³C₅H₁₉N₆¹⁵NO₆

2687960-47-8

59-30-3

O=C1C2=NC(CNC3=CC=C(C=C3)C([15NH][13C@H]([13C](O)=O)[13CH2][13CH2][13C](O)=O)=O)=CNC2=NC(N)=N1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-233.  [Content Brief]